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The role of early growth response 1 (EGR1) in brain plasticity and neuropsychiatric disorders
It is now clearly established that complex interactions between genes and environment are
involved in multiple aspects of neuropsychiatric disorders, from determining an individual's …
involved in multiple aspects of neuropsychiatric disorders, from determining an individual's …
Therapeutic potential of microRNA in tendon injuries
Introduction The regulatory role of microRNA (miRNA) in several conditions has been
studied, but their function in tendon healing remains elusive. This review summarizes how …
studied, but their function in tendon healing remains elusive. This review summarizes how …
EGR1 transcription factor is a multifaceted regulator of matrix production in tendons and other connective tissues
E Havis, D Duprez - International journal of molecular sciences, 2020 - mdpi.com
Although the transcription factor EGR1 is known as NGF1-A, TIS8, Krox24, zif/268, and
ZENK, it still has many fewer names than biological functions. A broad range of signals …
ZENK, it still has many fewer names than biological functions. A broad range of signals …
Macrophage-derived miRNA-containing exosomes induce peritendinous fibrosis after tendon injury through the miR-21-5p/Smad7 pathway
Following tendon injury, the development of fibrotic healing response impairs tendon
function and restricts tendon motion. Peritendinous tissue fibrosis poses a major clinical …
function and restricts tendon motion. Peritendinous tissue fibrosis poses a major clinical …
Tendon tissue engineering: Current progress towards an optimized tenogenic differentiation protocol for human stem cells
Tendons are integral to our daily lives by allowing movement and locomotion but are
frequently injured, leading to patient discomfort and impaired mobility. Current clinical …
frequently injured, leading to patient discomfort and impaired mobility. Current clinical …
The functions and mechanisms of tendon stem/progenitor cells in tendon healing
J Lu, H Chen, K Lyu, L Jiang, Y Chen… - Stem Cells …, 2023 - Wiley Online Library
Tendon injury is one of the prevalent disorders of the musculoskeletal system in orthopedics
and is characterized by pain and limitation of joint function. Due to the difficulty of …
and is characterized by pain and limitation of joint function. Due to the difficulty of …
RNA binding candidates for human ADAR3 from substrates of a gain of function mutant expressed in neuronal cells
Human ADAR3 is a catalytically inactive member of the Adenosine Deaminase Acting on
RNA (ADAR) protein family, whose active members catalyze A-to-I RNA editing in …
RNA (ADAR) protein family, whose active members catalyze A-to-I RNA editing in …
Long noncoding RNA H19 accelerates tenogenic differentiation and promotes tendon healing through targeting miR‐29b‐3p and activating TGF‐β1 signaling
Tendon injures are common orthopedic conditions, but tendon development and the
pathogenesis of tendon injures, such as tendinopathy, remain largely unknown and have …
pathogenesis of tendon injures, such as tendinopathy, remain largely unknown and have …
Biology of tendon stem cells and tendon in aging
Both tendon injuries and tendinopathies, particularly rotator cuff tears, increase with tendon
aging. Tendon stem cells play important roles in promoting tendon growth, maintenance …
aging. Tendon stem cells play important roles in promoting tendon growth, maintenance …
The role of MicroRNAs in tendon injury, repair, and related tissue engineering
Tendon injuries are one of the most common musculoskeletal disorders that cause
considerable morbidity and significantly compromise the patients' quality of life. The innate …
considerable morbidity and significantly compromise the patients' quality of life. The innate …