The type VI secretion system of Vibrio cholerae fosters horizontal gene transfer

S Borgeaud, LC Metzger, T Scrignari, M Blokesch - Science, 2015 - science.org
Natural competence for transformation is a common mode of horizontal gene transfer and
contributes to bacterial evolution. Transformation occurs through the uptake of external DNA …

Combating cholera

BY Hsueh, CM Waters - F1000Research, 2019 - pmc.ncbi.nlm.nih.gov
Cholera infections caused by the gamma-proteobacterium Vibrio cholerae have ravaged
human populations for centuries, and cholera pandemics have afflicted every corner of the …

Effects of intestinal microbiota on physiological metabolism and pathogenicity of Vibrio

H Sun, C Zhu, X Fu, S Khattak, J Wang, Z Liu… - Frontiers in …, 2022 - frontiersin.org
Vibrio species are disseminated broadly in the marine environment. Some of them can
cause severe gastroenteritis by contaminating seafood and drinking water, such as Vibrio …

Mobile phone data highlights the role of mass gatherings in the spreading of cholera outbreaks

F Finger, T Genolet, L Mari, GC de Magny… - Proceedings of the …, 2016 - pnas.org
The spatiotemporal evolution of human mobility and the related fluctuations of population
density are known to be key drivers of the dynamics of infectious disease outbreaks. These …

Bangladeshi children with acute diarrhoea show faecal microbiomes with increased Streptococcus abundance, irrespective of diarrhoea aetiology

S Kieser, SA Sarker, O Sakwinska… - Environmental …, 2018 - Wiley Online Library
We report streptococcal dysbiosis in acute diarrhoea irrespective of aetiology. Compared
with 20 healthy local controls, 71 Bangladeshi children hospitalized with acute diarrhoea …

Informing policy via dynamic models: Cholera in Haiti

J Wheeler, AE Rosengart, Z Jiang, K Tan… - PLOS Computational …, 2024 - journals.plos.org
Public health decisions must be made about when and how to implement interventions to
control an infectious disease epidemic. These decisions should be informed by data on the …

cAMP receptor protein controls Vibrio cholerae gene expression in response to host colonization

J Manneh-Roussel, JRJ Haycocks, A Magán… - MBio, 2018 - journals.asm.org
The bacterium Vibrio cholerae is native to aquatic environments and can switch lifestyles to
cause disease in humans. Lifestyle switching requires modulation of genetic systems for …

Ecological implications of gene regulation by TfoX and TfoY among diverse Vibrio species

LC Metzger, N Matthey, C Stoudmann… - Environmental …, 2019 - Wiley Online Library
Bacteria of the genus Vibrio are common members of aquatic environments where they
compete with other prokaryotes and defend themselves against grazing predators. A …

Sewage promotes Vibrio vulnificus growth and alters gene transcription in Vibrio vulnificus CMCP6

JW Conrad, VJ Harwood - Microbiology spectrum, 2022 - journals.asm.org
Vibrio vulnificus is a naturally occurring, potentially lethal pathogen found in coastal waters,
fish, and shellfish. Sewage spills in coastal waters occur when infrastructure fails due to …

Circulation of a quorum-sensing-impaired variant of Vibrio cholerae strain C6706 masks important phenotypes

S Stutzmann, M Blokesch - MSphere, 2016 - journals.asm.org
Vibrio cholerae, the causative agent of cholera, is a model organism for studying virulence
regulation, biofilm formation, horizontal gene transfer, and the cell-to-cell communication …