Therapeutic strategies for COVID-19: progress and lessons learned

G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …

The immunology of long COVID

DM Altmann, EM Whettlock, S Liu… - Nature Reviews …, 2023 - nature.com
Long COVID is the patient-coined term for the disease entity whereby persistent symptoms
ensue in a significant proportion of those who have had COVID-19, whether asymptomatic …

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and …

AJ Ferrari, DF Santomauro, A Aali, YH Abate… - The Lancet, 2024 - thelancet.com
Background Detailed, comprehensive, and timely reporting on population health by
underlying causes of disability and premature death is crucial to understanding and …

[HTML][HTML] Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study …

JD Steinmetz, KM Seeher, N Schiess… - The Lancet …, 2024 - thelancet.com
Background Disorders affecting the nervous system are diverse and include
neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions …

Postacute sequelae of COVID-19 at 2 years

B Bowe, Y **e, Z Al-Aly - Nature medicine, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can lead to
postacute sequelae in multiple organ systems, but evidence is mostly limited to the first year …

Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021

SE Vollset, HS Ababneh, YH Abate, C Abbafati… - The Lancet, 2024 - thelancet.com
Background Future trends in disease burden and drivers of health are of great interest to
policy makers and the public at large. This information can be used for policy and long-term …

Postacute sequelae of SARS-CoV-2 infection in the pre-delta, delta, and omicron eras

Y **e, T Choi, Z Al-Aly - New England Journal of Medicine, 2024 - Mass Medical Soc
Background Postacute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection (PASC) can affect many organ systems. However, temporal changes during …

[HTML][HTML] Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and …

AE Schumacher, HH Kyu, A Aali, C Abbafati, J Abbas… - The Lancet, 2024 - thelancet.com
Background Estimates of demographic metrics are crucial to assess levels and trends of
population health outcomes. The profound impact of the COVID-19 pandemic on …

Persistent complement dysregulation with signs of thromboinflammation in active Long Covid

C Cervia-Hasler, SC Brüningk, T Hoch, B Fan, G Muzio… - Science, 2024 - science.org
Long Covid is a debilitating condition of unknown etiology. We performed multimodal
proteomics analyses of blood serum from COVID-19 patients followed up to 12 months after …

Risk factors associated with post− COVID-19 condition: a systematic review and meta-analysis

V Tsampasian, H Elghazaly… - JAMA internal …, 2023 - jamanetwork.com
Importance Post− COVID-19 condition (PCC) is a complex heterogeneous disorder that has
affected the lives of millions of people globally. Identification of potential risk factors to better …