I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

This systematic review evaluates the efficacy and safety of biologicals for chronic
rhinosinusitis with nasal polyps (CRSwNP) compared with the standard of care. PubMed …

Objective The minimal clinically important difference (MCID) of a patient-reported outcome
measure (PROM) represents a threshold value of change in PROM score deemed to have …

Background Dupilumab, a monoclonal anti‐IL‐4Rα antibody, is approved for several type 2
mediated inflammatory diseases like asthma, atopic dermatitis, and diffuse type 2 chronic …

Background Systemic corticosteroids (SCSs) are associated with short-and long-term
adverse effects. Objective To assess mepolizumab efficacy according to prior SCS use and …

Objective Treatment for chronic rhinosinusitis with nasal polyps (CRSwNP) generally
involves intranasal corticosteroids (INCS) and saline irrigation, followed by short courses of …

Background Quality of life (QOL) for individuals with sinonasal malignancy (SNM) is
significantly under‐studied, yet it is critical for counseling and may impact treatment. In this …

Background: With the recent proliferation of novel therapeutics for chronic rhinosinusitis with
nasal polyps (CRSwNP), there is an immediate need for comprehensive means to assess …

Objective To determine the impact of comorbid migraine on quality of life (QOL) in chronic
rhinosinusitis (CRS). Methods A total of 213 adult patients with CRS were recruited. All …

Objective To evaluate the contribution of postnasal drip (PND) and chronic cough (CC) to
symptoms of patients with chronic rhinitis treated with temperature‐controlled …