The complement system: an unexpected role in synaptic pruning during development and disease
AH Stephan, BA Barres… - Annual review of …, 2012 - annualreviews.org
An unexpected role for the classical complement cascade in the elimination of central
nervous system (CNS) synapses has recently been discovered. Complement proteins are …
nervous system (CNS) synapses has recently been discovered. Complement proteins are …
The role of the novel adipocyte-derived hormone adiponectin in human disease
JJ Diez, P Iglesias - European Journal of endocrinology, 2003 - academic.oup.com
Abstract Adiponectin, also called GBP-28, apM1, AdipoQ and Acrp30, is a novel adipose
tIssue-specific protein that has structural homology to collagen VIII and X and complement …
tIssue-specific protein that has structural homology to collagen VIII and X and complement …
Complement is activated by IgG hexamers assembled at the cell surface
Complement activation by antibodies bound to pathogens, tumors, and self antigens is a
critical feature of natural immune defense, a number of disease processes, and …
critical feature of natural immune defense, a number of disease processes, and …
[書籍][B] Wintrobe's clinical hematology
MM Wintrobe - 2008 - books.google.com
Now available in a thoroughly revised Twelfth Edition, Wintrobe's Clinical Hematology
continues to be an industry leader with its ability to correlate basic science with the clinical …
continues to be an industry leader with its ability to correlate basic science with the clinical …
Adipo‐myokines: Two sides of the same coin—Mediators of inflammation and mediators of exercise
S Raschke, J Eckel - Mediators of inflammation, 2013 - Wiley Online Library
This review summarizes the current literature regarding the most discussed contraction‐
regulated moykines like IL‐6, IL‐15, irisin, BDNF, ANGPTL4, FGF21, myonectin and MCP‐1 …
regulated moykines like IL‐6, IL‐15, irisin, BDNF, ANGPTL4, FGF21, myonectin and MCP‐1 …
ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism
In recent years, we have learned that adipocytes are not merely inert storage depots for
triglycerides but rather highly active cells with potent autocrine, paracrine and endocrine …
triglycerides but rather highly active cells with potent autocrine, paracrine and endocrine …
The molecular architecture of the TNF superfamily
JL Bodmer, P Schneider, J Tschopp - Trends in biochemical sciences, 2002 - cell.com
Ligands of the TNF (tumour necrosis factor) superfamily have pivotal roles in the
organization and function of the immune system, and are implicated in the aetiology of …
organization and function of the immune system, and are implicated in the aetiology of …
Preclinical Activity of the Type II CD20 Antibody GA101 (Obinutuzumab) Compared with Rituximab and Ofatumumab In Vitro and in Xenograft Models
S Herter, F Herting, O Mundigl, I Waldhauer… - Molecular cancer …, 2013 - AACR
We report the first preclinical in vitro and in vivo comparison of GA101 (obinutuzumab), a
novel glycoengineered type II CD20 monoclonal antibody, with rituximab and ofatumumab …
novel glycoengineered type II CD20 monoclonal antibody, with rituximab and ofatumumab …
Recent advances on the complement system of teleost fish
H Boshra, J Li, JO Sunyer - Fish & shellfish immunology, 2006 - Elsevier
The complement system plays an essential role in alerting the host of the presence of
potential pathogens, as well as in their clearing. In addition, activation of the complement …
potential pathogens, as well as in their clearing. In addition, activation of the complement …
Evolution of the lectin–complement pathway and its role in innate immunity
T Fujita - Nature Reviews Immunology, 2002 - nature.com
Discrimination between self and non-self by lectins (carbohydrate-binding proteins) is a
strategy of innate immunity that is found in both vertebrates and invertebrates. In vertebrates …
strategy of innate immunity that is found in both vertebrates and invertebrates. In vertebrates …