Treatment options for motor and non-motor symptoms of Parkinson's disease

FC Church - Biomolecules, 2021 - mdpi.com
Parkinson's disease (PD) usually presents in older adults and typically has both motor and
non-motor dysfunctions. PD is a progressive neurodegenerative disorder resulting from …

Current and future directions of deep brain stimulation for neurological and psychiatric disorders: JNSPG 75th Anniversary Invited Review Article

DJ Lee, CS Lozano, RF Dallapiazza… - Journal of neurosurgery, 2019 - thejns.org
Deep brain stimulation (DBS) has evolved considerably over the past 4 decades. Although it
has primarily been used to treat movement disorders such as Parkinson's disease, essential …

Deep brain stimulation for the management of refractory neurological disorders: a comprehensive review

JP Rissardo, NM Vora, I Tariq, A Mujtaba, ALF Caprara - Medicina, 2023 - mdpi.com
In recent decades, deep brain stimulation (DBS) has been extensively studied due to its
reversibility and significantly fewer side effects. DBS is mainly a symptomatic therapy, but the …

Applications of microwaves in medicine

JC Chiao, C Li, J Lin, RH Caverly… - IEEE Journal of …, 2022 - ieeexplore.ieee.org
Advances and updates in medical applications utilizing microwave techniques and
technologies are reviewed in this paper. The article aims to provide an overview of enablers …

Neuronal and synaptic adaptations underlying the benefits of deep brain stimulation for Parkinson's disease

W Xu, J Wang, XN Li, J Liang, L Song, Y Wu… - Translational …, 2023 - Springer
Deep brain stimulation (DBS) is a well-established and effective treatment for patients with
advanced Parkinson's disease (PD), yet its underlying mechanisms remain enigmatic …

[HTML][HTML] Personalized and circuit-based transcranial magnetic stimulation: Evidence, controversies, and opportunities

RFH Cash, A Zalesky - Biological Psychiatry, 2024 - Elsevier
The development of neuroimaging methodologies to map brain connectivity has transformed
our understanding of psychiatric disorders, the distributed effects of brain stimulation, and …

T‐type calcium channels as therapeutic targets in essential tremor and Parkinson's disease

LG Matthews, CB Puryear, SS Correia… - Annals of Clinical …, 2023 - Wiley Online Library
Neuronal action potential firing patterns are key components of healthy brain function.
Importantly, restoring dysregulated neuronal firing patterns has the potential to be a …

[HTML][HTML] Acute low frequency dorsal subthalamic nucleus stimulation improves verbal fluency in Parkinson's disease

DJ Lee, NM Drummond, U Saha, P De Vloo… - Brain Stimulation, 2021 - Elsevier
Background Parkinson's disease (PD) is a common neurodegenerative disorder that results
in movement-related dysfunction and has variable cognitive impairment. Deep brain …

Longitudinal follow up of data‐driven cognitive subtypes in Parkinson's disease

D Pourzinal, J Yang, K Sivakumaran… - Brain and …, 2023 - Wiley Online Library
Aim The dual syndrome hypothesis proposes that there are two cognitive subtypes in
Parkinson's disease (PD): a frontal subtype with executive/attention impairment and gradual …

Patients with cognitive impairment in Parkinson's disease benefit from deep brain stimulation: a case‐control study

CK Block, M Patel, BB Risk, E Staikova… - Movement Disorders …, 2023 - Wiley Online Library
Background Deep brain stimulation (DBS) for Parkinson's disease (PD) is generally
contraindicated in persons with dementia but it is frequently performed in people with mild …