Light-powered catalysis has found broad utility as a chemical transformation strategy, with
widespread impact on energy, environment, drug discovery and human health. A noteworthy …

A new biocompatible strategy for photoinduced DNA interstrand cross-linking is presented.
Methylene blue induced 1O2 formation triggers furan oxidation; the resulting aldehyde then …

Biomedical research has been empowered by tools that enable spatial and temporal control
of biological systems. These have predominantly come from photocaged bioactive …

Furan mediated nucleic acid cross-linking, initially developed for DNA interstrand duplex
cross-linking, has matured into a versatile tool for the study of protein and nucleic acid …

Abstract G‐quadruplexes (G4 s) are secondary, tetraplexed DNA structures abundant in non‐
coding regions of the genome, implicated in gene transcription processes and currently …

The site‐selective introduction of photo‐crosslinking groups into proteins enables the
discovery and map** of weak and/or transient protein interactions with high …

Heterodimeric interstrand cross-linked DNA was constructed by the “bis-click” reaction
carried out on preformed oligonucleotide duplexes with the bis-azide 1. For this, alkynylated …

We here report on the furan oxidation methodology for interstrand cross-linking of RNA
duplexes, which have a different structure and are more stiff, reactive and labile than their …

Oligonucleotides (ODNs) find applications as diagnostic and therapeutic tools due to their
unique ability to interact, thanks to Watson-Crick base pairing, with a specific DNA or RNA …

Phosphazene chemistry continues to expand in its breadth and application. This article
discusses new research published in 2013 covering mono-and dimeric structures …