Integrated continuous pharmaceutical technologies—a review
Innovation in the pharmaceutical industry has been limited for a long time to the research
and development of new active compounds; meanwhile, the structure of the production …
and development of new active compounds; meanwhile, the structure of the production …
Near-infrared spectroscopic applications in pharmaceutical particle technology
M Razuc, A Grafia, L Gallo… - Drug Development …, 2019 - Taylor & Francis
Near-infrared spectroscopy (NIRS) is nowadays an established analytical technique in the
pharmaceutical industry. The aim of this review is to present the progress of NIRS in …
pharmaceutical industry. The aim of this review is to present the progress of NIRS in …
Recent progress in continuous and semi-continuous processing of solid oral dosage forms: a review
Context: Continuous processing is an innovative production concept well known and
successfully used in other industries for many years. The modern pharmaceutical industry is …
successfully used in other industries for many years. The modern pharmaceutical industry is …
Process analytical technology in continuous manufacturing of a commercial pharmaceutical product
JM Vargas, S Nielsen, V Cárdenas, A Gonzalez… - International journal of …, 2018 - Elsevier
The implementation of process analytical technology and continuous manufacturing at an
FDA approved commercial manufacturing site is described. In this direct compaction process …
FDA approved commercial manufacturing site is described. In this direct compaction process …
[HTML][HTML] End-to-end continuous manufacturing of conventional compressed tablets: From flow synthesis to tableting through integrated crystallization and filtration
An end-to-end continuous pharmaceutical manufacturing process was developed for the
production of conventional direct compressed tablets on a proof-of-concept level for the first …
production of conventional direct compressed tablets on a proof-of-concept level for the first …
In-line Raman spectroscopic monitoring and feedback control of a continuous twin-screw pharmaceutical powder blending and tableting process
Abstract The integration of Process Analytical Technology (PAT) initiative into the continuous
production of pharmaceuticals is indispensable for reliable production. The present paper …
production of pharmaceuticals is indispensable for reliable production. The present paper …
Continuous powder feeding for pharmaceutical solid dosage form manufacture: a short review
CA Blackshields, AM Crean - Pharmaceutical development and …, 2018 - Taylor & Francis
There has been a noticeable shift from pharmaceutical batch processing towards a more
continuous mode of manufacture for solid oral dosage forms. Continuous solid oral dose …
continuous mode of manufacture for solid oral dosage forms. Continuous solid oral dose …
Sticking and picking in pharmaceutical tablet compression: an IQ consortium review
S Chattoraj, P Daugherity, T McDermott… - Journal of …, 2018 - Elsevier
Sticking and picking during tablet manufacture has received increasing interest recently, as
it causes tablet defects, downtime in manufacturing, and yield losses. The capricious nature …
it causes tablet defects, downtime in manufacturing, and yield losses. The capricious nature …
Design of the system to control a vibratory machine for mixing loose materials
Розроблено мехатронну систему для комплексної оцінки та адаптації експлуатаційних
параметрів вібраційної машини для приготування сипучих сумішей. Дана система …
параметрів вібраційної машини для приготування сипучих сумішей. Дана система …
Evaluation of analytical and sampling errors in the prediction of the active pharmaceutical ingredient concentration in blends from a continuous manufacturing process
JM Vargas, AD Roman-Ospino, E Sanchez… - Journal of …, 2017 - Springer
Purpose A near-infrared (NIR) spectroscopic method was developed for real time analysis of
the active pharmaceutical ingredient (API) in blends from a continuous manufacturing …
the active pharmaceutical ingredient (API) in blends from a continuous manufacturing …