Bioinformatic tools for microRNA dissection

MM Akhtar, L Micolucci, MS Islam, F Olivieri… - Nucleic acids …, 2016 - academic.oup.com
Recently, microRNAs (miRNAs) have emerged as important elements of gene regulatory
networks. MiRNAs are endogenous single-stranded non-coding RNAs (∼ 22-nt long) that …

Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes

A Montecalvo, AT Larregina… - Blood, The Journal …, 2012 - ashpublications.org
Dendritic cells (DCs) are the most potent APCs. Whereas immature DCs down-regulate T-
cell responses to induce/maintain immunologic tolerance, mature DCs promote immunity. To …

Web-based tools for miRNA studies analysis

F Shaker, A Nikravesh, R Arezumand… - Computers in biology …, 2020 - Elsevier
In recent years, thousands of microRNAs (miRNA) have been found in numerous species.
The huge data resulting from miRNA researches are ordered in several levels including …

miRPathDB 2.0: a novel release of the miRNA Pathway Dictionary Database

T Kehl, F Kern, C Backes, T Fehlmann… - Nucleic acids …, 2020 - academic.oup.com
Since the initial release of miRPathDB, tremendous progress has been made in the field of
microRNA (miRNA) research. New miRNA reference databases have emerged, a vast …

miRDB: a microRNA target prediction and functional annotation database with a wiki interface

X Wang - Rna, 2008 - rnajournal.cshlp.org
MicroRNAs (miRNAs) are short noncoding RNAs that are involved in the regulation of
thousands of gene targets. Recent studies indicate that miRNAs are likely to be master …

miRPathDB: a new dictionary on microRNAs and target pathways

C Backes, T Kehl, D Stöckel, T Fehlmann… - Nucleic acids …, 2016 - academic.oup.com
In the last decade, miRNAs and their regulatory mechanisms have been intensively studied
and many tools for the analysis of miRNAs and their targets have been developed. We …

MicroRNA 320a Functions as a Novel Endogenous Modulator of Aquaporins 1 and 4 as Well as a Potential Therapeutic Target in Cerebral Ischemia*[S]

S Sepramaniam, A Armugam, KY Lim… - Journal of Biological …, 2010 - ASBMB
Aquaporins facilitate efficient diffusion of water across cellular membranes, and water
homeostasis is critically important in conditions such as cerebral edema. Changes in …

MicroRNA and mRNA integrated analysis (MMIA): a web tool for examining biological functions of microRNA expression

S Nam, M Li, K Choi, C Balch, S Kim… - Nucleic acids …, 2009 - academic.oup.com
Abstract MicroRNAs (miRNAs) are small (19–24 nt), nonprotein-coding nucleic acids that
regulate specific 'target'gene products via hybridization to mRNA transcripts, resulting in …

Bioinformatics accelerates the major tetrad: a real boost for the pharmaceutical industry

T Behl, I Kaur, A Sehgal, S Singh, S Bhatia… - International Journal of …, 2021 - mdpi.com
With advanced technology and its development, bioinformatics is one of the avant-garde
fields that has managed to make amazing progress in the pharmaceutical–medical field by …

Noncoding RNAs databases: current status and trends

V Maracaja-Coutinho, AR Paschoal… - … biology of non-coding …, 2019 - Springer
One of the most important resources for researchers of noncoding RNAs is the information
available in public databases spread over the internet. However, the effective exploration of …