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[HTML][HTML] Polygenic causes of congenital diaphragmatic hernia produce common lung pathologies
Congenital diaphragmatic hernia (CDH) is one of the most common and lethal congenital
anomalies, and significant evidence is available in support of a genetic contribution to its …
anomalies, and significant evidence is available in support of a genetic contribution to its …
Fetal hypoplastic lungs have multilineage inflammation that is reversed by amniotic fluid stem cell extracellular vesicle treatment
Antenatal administration of extracellular vesicles from amniotic fluid stem cells (AFSC-EVs)
reverses features of pulmonary hypoplasia in models of congenital diaphragmatic hernia …
reverses features of pulmonary hypoplasia in models of congenital diaphragmatic hernia …
Pulmonary vascular development in congenital diaphragmatic hernia
DS Mous, HM Kool, R Wijnen… - European …, 2018 - publications.ersnet.org
Congenital diaphragmatic hernia (CDH) is a rare congenital anomaly characterised by a
diaphragmatic defect, persistent pulmonary hypertension (PH) and lung hypoplasia. The …
diaphragmatic defect, persistent pulmonary hypertension (PH) and lung hypoplasia. The …
Fetal lung underdevelopment is rescued by administration of amniotic fluid stem cell extracellular vesicles in rodents
Fetal lung underdevelopment, also known as pulmonary hypoplasia, is characterized by
decreased lung growth and maturation. The most common birth defect found in babies with …
decreased lung growth and maturation. The most common birth defect found in babies with …
Prenatal microRNA miR-200b therapy improves nitrofen-induced pulmonary hypoplasia associated with congenital diaphragmatic hernia
N Khoshgoo, R Kholdebarin, P Pereira-Terra… - Annals of …, 2019 - journals.lww.com
Objective: We aimed to evaluate the use of miR-200b as a prenatal transplacental therapy in
the nitrofen rat model of abnormal lung development and congenital diaphragmatic hernia …
the nitrofen rat model of abnormal lung development and congenital diaphragmatic hernia …
Proteomic profiling of hypoplastic lungs suggests an underlying inflammatory response in the pathogenesis of abnormal lung development in congenital …
The pathogenesis of lung hypoplasia in congenital diaphragmatic hernia (CDH), a common
birth defect, is poorly understood. The diaphragmatic defect can be repaired surgically, but …
birth defect, is poorly understood. The diaphragmatic defect can be repaired surgically, but …
Basic and translational science advances in congenital diaphragmatic hernia
Abstract Congenital Diaphragmatic Hernia (CDH) is a birth defect that is characterized by
lung hypoplasia, pulmonary hypertension and a diaphragmatic defect that allows herniation …
lung hypoplasia, pulmonary hypertension and a diaphragmatic defect that allows herniation …
Characterization of extracellular vesicles derived from cardiac cells in an in vitro model of preconditioning
S Borosch, E Dahmen, C Beckers… - Journal of …, 2017 - Taylor & Francis
Preconditioning is a promising technique to protect the heart from ischaemia-reperfusion
injury. In this context, the crosstalk between different cardiac cell types and especially the …
injury. In this context, the crosstalk between different cardiac cell types and especially the …
Malarial PI4K inhibitor induced diaphragmatic hernias in rat: potential link with mammalian kinase inhibition
C Demarta‐Gatsi, C Donini, J Duffy… - Birth Defects …, 2022 - Wiley Online Library
Background MMV390048 is an aminopyridine plasmodial PI4K inhibitor, selected as a
Plasmodium blood‐stage schizonticide for a next generation of malaria treatments to …
Plasmodium blood‐stage schizonticide for a next generation of malaria treatments to …
Fetal lung regeneration using stem cell‐derived extracellular vesicles: A new frontier for pulmonary hypoplasia secondary to congenital diaphragmatic hernia
The poor outcomes of babies with congenital diaphragmatic hernia (CDH) are directly
related to pulmonary hypoplasia, a condition characterized by impaired lung development …
related to pulmonary hypoplasia, a condition characterized by impaired lung development …