Cartilage homeostasis is governed by articular chondrocytes via their ability to modulate
extracellular matrix production and degradation. In turn, chondrocyte activity is regulated by …

Kinase activation and phosphorylation cascades are key to initiate immune cell activation in
response to recognition of antigen and sensing of microbial danger. However, for balanced …

An incomplete understanding of the molecular mechanisms behind impairment of lung
pathobiology by COVID-19 complicates its clinical management. In this study, we analyzed …

Cancer is one of the most diagnosed diseases in developed countries. Inflammation is a
common response to different stress situations including cancer and infection. In those …

Viral infections are a common cause of asthma exacerbations, with human rhinoviruses (RV)
the most common trigger. RV signals through a number of different receptors, including toll …

Cholangiocarcinoma is a deadly cancer worldwide, associated with a poor prognosis and
limited therapeutic options. Although cholangiocarcinoma accounts for less than 15% of liver …

Airway epithelial cells, which lines the respiratory mucosa is in direct contact with the
environment. Airway epithelial cells are the primary target for rhinovirus and other inhaled …

Nile tilapia (Oreochromis niloticus) is one of the most important aquaculture species farmed
worldwide. However, the recent emergence of tilapia lake virus (TiLV) disease, also known …

Osteoarthritis (OA) is a degenerative joint disease characterized by irreversible cartilage
damage, inflammation and altered chondrocyte phenotype. Transforming growth factor-β …

Abstract Background Pathogenic coronaviruses include Middle East respiratory syndrome
coronavirus (MERS-CoV), severe acute respiratory syndrome coronavirus (SARS-CoV), and …