The regulation of cartilage extracellular matrix homeostasis in joint cartilage degeneration and regeneration

Z Peng, H Sun, V Bunpetch, Y Koh, Y Wen, D Wu… - Biomaterials, 2021 - Elsevier
Osteoarthritis (OA) is a major cause of disability and socioeconomic loss worldwide.
However, the current pharmacological approaches used to treat OA are largely palliative …

Review of synthetic and hybrid scaffolds in cartilage tissue engineering

M Wasyłeczko, W Sikorska, A Chwojnowski - Membranes, 2020 - mdpi.com
Cartilage tissue is under extensive investigation in tissue engineering and regenerative
medicine studies because of its limited regenerative potential. Currently, many scaffolds are …

Agarose-based biomaterials: opportunities and challenges in cartilage tissue engineering

MA Salati, J Khazai, AM Tahmuri, A Samadi… - Polymers, 2020 - mdpi.com
The lack of adequate blood/lymphatic vessels as well as low-potential articular cartilage
regeneration underlines the necessity to search for alternative biomaterials. Owing to their …

[HTML][HTML] Designing functional hyaluronic acid-based hydrogels for cartilage tissue engineering

M Wang, Z Deng, Y Guo, P Xu - Materials Today Bio, 2022 - Elsevier
Damage to cartilage tissues is often difficult to repair owing to chronic inflammation and a
lack of bioactive factors. Therefore, develo** bioactive materials, such as hydrogels acting …

Advances in hybrid fabrication toward hierarchical tissue constructs

PD Dalton, TBF Woodfield, V Mironov… - Advanced …, 2020 - Wiley Online Library
The diversity of manufacturing processes used to fabricate 3D implants, scaffolds, and tissue
constructs is continuously increasing. This growing number of different applicable fabrication …

Fabrication of chitosan/agarose scaffolds containing extracellular matrix for tissue engineering applications

SS Garakani, M Khanmohammadi, Z Atoufi… - International journal of …, 2020 - Elsevier
One of the most effective approaches for treatment of cartilage involves the use of porous
three-dimensional scaffolds, which are useful for improving not only cellular adhesion but …

Exercise for osteoarthritis: a literature review of pathology and mechanism

H Kong, XQ Wang, XA Zhang - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Osteoarthritis (OA) has a very high incidence worldwide and has become a very common
joint disease in the elderly. Currently, the treatment methods for OA include surgery, drug …

Injectable PNIPAM/Hyaluronic acid hydrogels containing multipurpose modified particles for cartilage tissue engineering: Synthesis, characterization, drug release …

Z Atoufi, SK Kamrava, SM Davachi… - International journal of …, 2019 - Elsevier
Novel injectable thermosensitive PNIPAM/hyaluronic acid hydrogels containing various
amounts of chitosan-g-acrylic acid coated PLGA (ACH-PLGA) micro/nanoparticles were …

Design and engineering of organ-on-a-chip

S Cho, S Lee, SI Ahn - Biomedical engineering letters, 2023 - Springer
Abstract Organ-on-a-chip (OOC) is an emerging interdisciplinary technology that
reconstitutes the structure, function, and physiology of human tissues as an alternative to …

Engineering a highly biomimetic chitosan-based cartilage scaffold by using short fibers and a cartilage-decellularized matrix

Y Shen, Y Xu, B Yi, X Wang, H Tang, C Chen… - …, 2021 - ACS Publications
Engineering scaffolds with structurally and biochemically biomimicking cues is essential for
the success of tissue-engineered cartilage. Chitosan (CS)-based scaffolds have been widely …