Mammalian cell membranes are composed of a complex array of glycerophospholipids and
sphingolipids that vary in head-group and acyl-chain composition. In a given cell type …

Knowledge of the structure and dynamics of membranes has traditionally been fragmentary
at the atomic level. This is due partly to the fluid character of membranes under physiological …

Without any exaggeration, cholesterol is one of the most important lipid species in eukaryotic
cells. Its effects on cellular membranes and functions range from purely mechanistic to …

Low density lipoprotein (LDL) particles are the major cholesterol carriers in circulation and
their physiological function is to carry cholesterol to the cells. In the process of atherogenesis …

To investigate the microscopic interactions between cholesterol and lipids in biological
membranes, we have performed a series of molecular dynamics simulations of large …

The existence of relatively large and long-lived detergent-insoluble, sphingolipid-and
cholesterol-enriched, liquid-ordered lipid raft domains in the plasma membranes of …

Sphingomyelin and phosphatidylcholine are important components in the external leaflet of
cellular plasma membranes. In this review we compare the structure of these lipid …

Atomic force microscopy has been used to study the distribution of ganglioside GM1 in
model membranes composed of ternary lipid mixtures that mimic the composition of lipid …

Lipid packing is a crucial feature of cellular membranes. Quantitative analysis of membrane
lipid packing can be achieved using polarity sensitive probes whose emission spectrum …

By using molecular dynamics simulation technique we studied the changes occurring in
membranes constructed of dipalmitoylphosphatidylcholine (DPPC) and cholesterol at 8: 1 …