Hallmarks of response, resistance, and toxicity to immune checkpoint blockade
G Morad, BA Helmink, P Sharma, JA Wargo - Cell, 2021 - cell.com
Unprecedented advances have been made in cancer treatment with the use of immune
checkpoint blockade (ICB). However, responses are limited to a subset of patients, and …
checkpoint blockade (ICB). However, responses are limited to a subset of patients, and …
Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …
exercise training are a potent stimulus for physiological adaptation in many organs …
Health and disease markers correlate with gut microbiome composition across thousands of people
Variation in the human gut microbiome can reflect host lifestyle and behaviors and influence
disease biomarker levels in the blood. Understanding the relationships between gut …
disease biomarker levels in the blood. Understanding the relationships between gut …
Understanding the role of the gut microbiome and microbial metabolites in non-alcoholic fatty liver disease: current evidence and perspectives
N Vallianou, GS Christodoulatos, I Karampela… - Biomolecules, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide. NAFLD begins as a relatively benign hepatic steatosis which can evolve to non …
worldwide. NAFLD begins as a relatively benign hepatic steatosis which can evolve to non …
From gut microbiota to host appetite: gut microbiota-derived metabolites as key regulators
H Han, B Yi, R Zhong, M Wang, S Zhang, J Ma, Y Yin… - Microbiome, 2021 - Springer
Feelings of hunger and satiety are the key determinants for maintaining the life of humans
and animals. Disturbed appetite control may disrupt the metabolic health of the host and …
and animals. Disturbed appetite control may disrupt the metabolic health of the host and …
[HTML][HTML] The compelling link between physical activity and the body's defense system
This review summarizes research discoveries within 4 areas of exercise immunology that
have received the most attention from investigators:(1) acute and chronic effects of exercise …
have received the most attention from investigators:(1) acute and chronic effects of exercise …
[HTML][HTML] Interplay between exercise and gut microbiome in the context of human health and performance
Gut microbiota and exercise have recently been shown to be interconnected. Both moderate
and intense exercise are typically part of the training regimen of endurance athletes, but they …
and intense exercise are typically part of the training regimen of endurance athletes, but they …
Influence of the gut microbiome, diet, and environment on risk of colorectal cancer
Researchers have discovered associations between elements of the intestinal microbiome
(including specific microbes, signaling pathways, and microbiota-related metabolites) and …
(including specific microbes, signaling pathways, and microbiota-related metabolites) and …
The human gut microbiome: from association to modulation
Our understanding of the human gut microbiome continues to evolve at a rapid pace, but
practical application of thisknowledge is still in its infancy. This review discusses the type of …
practical application of thisknowledge is still in its infancy. This review discusses the type of …
Gut microbiota-derived short-chain fatty acids and colorectal cancer: Ready for clinical translation?
H Hou, D Chen, K Zhang, W Zhang, T Liu, S Wang… - Cancer Letters, 2022 - Elsevier
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of
cancer-related death worldwide. It involves the complex interactions between genetic …
cancer-related death worldwide. It involves the complex interactions between genetic …