Genetic load: genomic estimates and applications in non-model animals

G Bertorelle, F Raffini, M Bosse, C Bortoluzzi… - Nature Reviews …, 2022 - nature.com
Genetic variation, which is generated by mutation, recombination and gene flow, can reduce
the mean fitness of a population, both now and in the future. This 'genetic load'has been …

Global genetic diversity status and trends: towards a suite of Essential Biodiversity Variables (EBVs) for genetic composition

S Hoban, FI Archer, LD Bertola, JG Bragg… - Biological …, 2022 - Wiley Online Library
Biodiversity underlies ecosystem resilience, ecosystem function, sustainable economies,
and human well‐being. Understanding how biodiversity sustains ecosystems under …

[HTML][HTML] Genetic diversity targets and indicators in the CBD post-2020 Global Biodiversity Framework must be improved

S Hoban, M Bruford, JDU Jackson… - Biological …, 2020 - Elsevier
The 196 parties to the Convention on Biological Diversity (CBD) will soon agree to a post-
2020 global framework for conserving the three elements of biodiversity (genetic, species …

Conservation genetics as a management tool: The five best-supported paradigms to assist the management of threatened species

Y Willi, TN Kristensen, CM Sgrò… - Proceedings of the …, 2022 - National Acad Sciences
About 50 y ago, Crow and Kimura [An Introduction to Population Genetics Theory (1970)]
and Ohta and Kimura [Genet. Res. 22, 201–204 (1973)] laid the foundations of conservation …

The inflated significance of neutral genetic diversity in conservation genetics

JC Teixeira, CD Huber - Proceedings of the National …, 2021 - National Acad Sciences
The current rate of species extinction is rapidly approaching unprecedented highs, and life
on Earth presently faces a sixth mass extinction event driven by anthropogenic activity …

Post-2020 biodiversity targets need to embrace climate change

A Arneth, YJ Shin, P Leadley… - Proceedings of the …, 2020 - National Acad Sciences
Recent assessment reports by the Intergovernmental Panel on Climate Change (IPCC) and
the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services …

Genetic rescue: A critique of the evidence supports maximizing genetic diversity rather than minimizing the introduction of putatively harmful genetic variation

K Ralls, P Sunnucks, RC Lacy, R Frankham - Biological Conservation, 2020 - Elsevier
Genetic rescue–ameliorating inbreeding depression and restoring genetic diversity of inbred
populations through gene flow-is valuable in wildlife conservation. Empirically validated …

Global protected areas seem insufficient to safeguard half of the world's mammals from human-induced extinction

DR Williams, C Rondinini… - Proceedings of the …, 2022 - National Acad Sciences
Protected areas (PAs) are a cornerstone of global conservation and central to international
plans to minimize global extinctions. During the coming century, global ecosystem …

Genetic rescue of small inbred populations: Meta‐analysis reveals large and consistent benefits of gene flow

R Frankham - Molecular ecology, 2015 - Wiley Online Library
Many species have fragmented distribution with small isolated populations suffering
inbreeding depression and/or reduced ability to evolve. Without gene flow from another …

Circling the drain: The extinction crisis and the future of humanity

R Dirzo, G Ceballos, PR Ehrlich - … Transactions of the …, 2022 - royalsocietypublishing.org
Humanity has triggered the sixth mass extinction episode since the beginning of the
Phanerozoic. The complexity of this extinction crisis is centred on the intersection of two …