Nucleic acids are emerging as powerful and functional biomaterials due to their molecular
recognition ability, programmability, and ease of synthesis and chemical modification …

DNA molecules utilize adenine, thymine, cytosine, and guanine for coding genetic
information. In addition to these four canonical nucleobases, DNA molecules also contain a …

An expedient [5+ 1] annulation method via Rh (III)-catalyzed C–H bond functionalization of
enaminones to synthesize polyaromatic rings is described. The reaction tolerates a broad …

5-Hydroxymethyluracil (5hmU) is found in the genomes of a diverse range of organisms as
another kind of 5-hydroxymethylpyrimidine, with the exception of 5-hydroxymethylcytosine …

Spatial positioning and proximity of relevant biomolecules such as DNA epigenetic marks
are fundamental to a deeper understanding of life. However, it remains poorly explored and …

Sensitive detection of gastric cancer-related biomarkers in human serum provides a
promising means for early cancer diagnosis. Herein, we report the design of a nucleic acid …

The identification of formylpyrimidines in DNA is crucial for a better understanding of
epigenetics. Although many techniques have been explored to detect their content, more …

Chemical modifications to nucleobases have a great influence on various cellular
processes, by making gene regulation more complex, thus indicating their profound impact …

Horseradish peroxidase (HRP) and fluorogen–dextran conjugate are tracers extensively
used for injection-based lineage tracing. However, HRP is sensitive to proteolytic digestion …

5-Formyluracil (5fU) based probes were designed and synthesized to detect Al3+ ions in
vitro and in biological systems. These probes were synthesised using furan-2 …