The immune system comprises diverse specialized cell types that cooperate to defend the
host against a wide range of pathogenic threats. Recent advancements in single-cell and …

The gut microbiome is crucial for nutrient metabolism, immune regulation, and intestinal
homeostasis with changes in its composition linked to complex diseases like inflammatory …

The growing availability of single-cell and spatially resolved transcriptomics has led to the
development of many approaches to infer cell–cell communication, each capturing only a …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system.
Inflammation is gradually compartmentalized and restricted to specific tissue niches such as …

The heterogeneous fiber type composition of skeletal muscle makes it challenging to
decipher the molecular signaling events driving the health-and performance benefits of …

The growing availability of single-cell and spatially-resolved transcriptomics has led to the
rapidly growing popularity of methods to infer cell-cell communication. Many approaches …

Toll-like receptors (TLRs) are critical components to stimulate immune responses against
various infections. Recently, TLR agonists have emerged as a promising way to activate anti …

Objectives Systemic lupus erythematosus (SLE) is characterised by systemic inflammation
involving various immune cell types. Monocytes, pivotal in promoting and regulating …

Anti-tumor immunity is crucial for high-grade serous ovarian cancer (HGSC) prognosis, yet
its adaptation upon standard chemotherapy remains poorly understood. Here, we conduct …

T follicular helper (Tfh) cells abundantly express the immunoreceptor programmed cell
death protein 1 (PD-1), and the impact of PD-1 deficiency on antibody (Ab)-mediated …