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Fluorescence image-guided tumour surgery
Intraoperative fluorescent imaging can provide real-time identification of tumours, lymph
nodes, nerves and other healthy and malignant tissues during oncological surgery …
nodes, nerves and other healthy and malignant tissues during oncological surgery …
Real-time fluorescence imaging in intraoperative decision making for cancer surgery
Fluorescence-guided surgery is an intraoperative optical imaging method that provides
surgeons with real-time guidance for the delineation of tumours. Currently, in phase 1 and 2 …
surgeons with real-time guidance for the delineation of tumours. Currently, in phase 1 and 2 …
Molecular engineering of activatable NIR-II hemicyanine reporters for early diagnosis and prognostic assessment of inflammatory bowel disease
Molecular imaging in the second near-infrared window (NIR-II) provides high-fidelity
visualization of biopathological events in deep tissue. However, most NIR-II probes produce …
visualization of biopathological events in deep tissue. However, most NIR-II probes produce …
Fluorescence lifetime of injected indocyanine green as a universal marker of solid tumours in patients
The surgical resection of solid tumours can be enhanced by fluorescence-guided imaging.
However, variable tumour uptake and incomplete clearance of fluorescent dyes reduces the …
However, variable tumour uptake and incomplete clearance of fluorescent dyes reduces the …
Molecular engineering of AIE luminogens for NIR-II/IIb bioimaging and surgical navigation of lymph nodes
Sentinel lymph node (SLN) imaging is vital for tumor staging and treatment decision-making,
and current methods for SLN imaging suffer from a short retention time, poor penetration …
and current methods for SLN imaging suffer from a short retention time, poor penetration …
Illuminating the future of precision cancer surgery with fluorescence imaging and artificial intelligence convergence
Real-time and accurate guidance for tumor resection has long been anticipated by
surgeons. In the past decade, the flourishing material science has made impressive …
surgeons. In the past decade, the flourishing material science has made impressive …
Bioorthogonally activatable cyanine dye with torsion-induced disaggregation for in vivo tumor imaging
Advancement of bioorthogonal chemistry in molecular optical imaging lies in expanding the
repertoire of fluorophores that can undergo fluorescence signal changes upon …
repertoire of fluorophores that can undergo fluorescence signal changes upon …
Targeted optical fluorescence imaging: a meta-narrative review and future perspectives
Purpose The aim of this review is to give an overview of the current status of targeted optical
fluorescence imaging in the field of oncology, cardiovascular, infectious and inflammatory …
fluorescence imaging in the field of oncology, cardiovascular, infectious and inflammatory …
Tumour-specific fluorescence-guided surgery for pancreatic cancer using panitumumab-IRDye800CW: a phase 1 single-centre, open-label, single-arm, dose …
Background Complete surgical resection remains the primary curative option for pancreatic
ductal adenocarcinoma, with positive margins in 30–70% of patients. In this study, we aimed …
ductal adenocarcinoma, with positive margins in 30–70% of patients. In this study, we aimed …
[HTML][HTML] First-in-human evaluation of a prostate-specific membrane antigen–targeted near-infrared fluorescent small molecule for fluorescence-based identification of …
Background Men with high-risk prostate cancer undergoing surgery likely recur due to
failure to completely excise regional and/or local disease. Objective The first-in-human …
failure to completely excise regional and/or local disease. Objective The first-in-human …