[HTML][HTML] Nanoparticles in cancer theragnostic and drug delivery: A comprehensive review

AN Al-Thani, AG Jan, M Abbas, M Geetha… - Life sciences, 2024 - Elsevier
This comprehensive review provides an in-depth analysis of how nanotechnology has
revolutionized cancer theragnostic, which combines diagnostic and therapeutic methods to …

[HTML][HTML] Recent Advances and Prospects of Nucleic Acid Therapeutics for Anti-Cancer Therapy

M Lee, M Lee, Y Song, S Kim, N Park - Molecules, 2024 - mdpi.com
Nucleic acid therapeutics are promising alternatives to conventional anti-cancer therapy,
such as chemotherapy and radiation therapy. While conventional therapies have limitations …

The application of aptamers in the repair of bone, nerve, and vascular tissues

YW Hsu, L Ma, Y Tang, M Li, C Zhou, Y Geng… - Journal of Materials …, 2025 - pubs.rsc.org
Aptamers represent a distinct category of short nucleotide sequences or peptide molecules
characterized by their ability to bind to specific targets with high precision. These molecules …

[HTML][HTML] Nanobodies' duo facilitates ultrasensitive serum HER-2/neu immunoassays via enhanced avidity interactions

S Boonkaew, L Teodori, MH Vendelbo, J Kjems… - Analytica Chimica …, 2025 - Elsevier
Background Existing liquid biopsy assays for protein biomarkers of cancer are mostly based
on antibodies (Ab) contributing unfavorably to their high cost. Easy to express and modify in …

Combination of adenosine blockade and ferroptosis for photo-immunotherapy of triple negative breast cancer with aptamer-modified copper sulfide

X Zhang, C Shi, Q Liu, Y Zhong, L Zhu… - Journal of Materials …, 2025 - pubs.rsc.org
Combination of immunotherapy and photothermal therapy (PTT) provides a promising
therapeutic performance for tumors. However, it still faces negative feedback from …

In silico selection of aptamers against SARS-CoV-2

AMA Shukri, SM Wang, C Feng, SL Chia, SFAM Nawi… - Analyst, 2024 - pubs.rsc.org
Aptamers are molecular recognition elements that have been extensively deployed in a
wide array of applications ranging from diagnostics to therapeutics. Due to their unique …

[HTML][HTML] In Silico Born Designed Anti-EGFR Aptamer Gol1 Has Anti-Proliferative Potential for Patient Glioblastoma Cells

A Golovin, F Dzarieva, K Rubetskaya… - International Journal of …, 2025 - mdpi.com
The epidermal growth factor receptor (EGFR) is one of the key oncomarkers in glioblastoma
(GB) biomedical research. High levels of EGFR expression and mutations have been found …

[HTML][HTML] Using Computer Modeling and Experimental Methods to Screen for Aptamers That Bind to the VV-GMCSF-LACT Virus

M Dymova, N Vasileva, D Malysheva, A Ageenko… - Molecules, 2024 - mdpi.com
Oncolytic virotherapy is a promising approach for cancer treatment. However, when
introduced into the body, the virus provokes the production of virus-neutralizing antibodies …

Dual roles of extracellular vesicles in acute lymphoblastic leukemia: implications for disease progression and theranostic strategies

MS Lajevardi, M Ashrafpour, SMH Mubarak… - Medical Oncology, 2025 - Springer
Abstract Acute Lymphoblastic Leukemia (ALL) is a heterogeneous blood cancer
characterized by the uncontrolled growth of immature lymphoid cells due to dysregulated …

[HTML][HTML] Towards Aptamer-Targeted Drug Delivery to Brain Tumors: The Synthesis of Ramified Conjugates of an EGFR-Specific Aptamer with MMAE on a Cathepsin B …

VA Brylev, EV Ryabukhina, EV Nazarova… - Pharmaceutics, 2024 - mdpi.com
Background/Objectives: Targeted delivery of chemotherapeutic agents is a well-established
approach to cancer therapy. Antibody–drug conjugates (ADCs) typically carry toxic payloads …