Traditional herbal medicine: Therapeutic potential in rheumatoid arthritis

Y Wang, S Chen, K Du, C Liang, S Wang… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Rheumatoid arthritis (RA) is a chronic inflammatory
autoimmune disease influenced by diverse endogenous and exogenous factors. It is …

Function of macrophages in disease: current understanding on molecular mechanisms

C Zhang, M Yang, AC Ericsson - Frontiers in immunology, 2021 - frontiersin.org
Tissue-resident macrophages (TRMs) are heterogeneous populations originating either
from monocytes or embryonic progenitors, and distribute in lymphoid and non-lymphoid …

Pathophysiology of systemic sclerosis: current understanding and new insights

M Cutolo, S Soldano, V Smith - Expert review of clinical …, 2019 - Taylor & Francis
ABSTRACT Introduction: Systemic sclerosis (SSc) is a complex autoimmune connective
tissue disease characterized by chronic and progressive tissue and organ fibrosis with …

Macrophage M1/M2 polarization and rheumatoid arthritis: a systematic review

S Tardito, G Martinelli, S Soldano, S Paolino… - Autoimmunity …, 2019 - Elsevier
Background and aim Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory
disease; the clinical manifestations are correlated with continuum multiarticular synovitis …

Targeting of CD163+ Macrophages in Inflammatory and Malignant Diseases

MK Skytthe, JH Graversen, SK Moestrup - International journal of …, 2020 - mdpi.com
The macrophage is a key cell in the pro-and anti-inflammatory response including that of the
inflammatory microenvironment of malignant tumors. Much current drug development in …

Macrophage: a cell with many faces and functions in tuberculosis

F Ahmad, A Rani, A Alam, S Zarin, S Pandey… - Frontiers in …, 2022 - frontiersin.org
Mycobacterium tuberculosis (Mtb) is the causative agent of human tuberculosis (TB) which
primarily infects the macrophages. Nearly a quarter of the world's population is infected …

Macrophage polarization in cardiac tissue repair following myocardial infarction

Y Kim, S Nurakhayev, A Nurkesh… - International journal of …, 2021 - mdpi.com
Cardiovascular disease is the leading cause of mortality and morbidity around the globe,
creating a substantial socio-economic burden as a result. Myocardial infarction is a …

Aging, inflammaging and immunosenescence as risk factors of severe COVID-19

AM Tizazu, HM Mengist, G Demeke - Immunity & Ageing, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease caused
by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is …

[HTML][HTML] Engineering homologous platelet-rich plasma, platelet-rich plasma-derived exosomes, and mesenchymal stem cell-derived exosomes-based dual …

BM Bakadia, AAQ Ahmed, L Lamboni, Z Shi… - Bioactive Materials, 2023 - Elsevier
The management of diabetic wounds remains a critical therapeutic challenge. Platelet-rich
plasma (PRP) gel, PRP-derived exosomes (PRP-Exos), and mesenchymal stem cell-derived …

Inhibition of estrogen signaling in myeloid cells increases tumor immunity in melanoma

B Chakraborty, J Byemerwa… - The Journal of …, 2021 - Am Soc Clin Investig
Immune checkpoint blockade (ICB) therapies have significantly prolonged patient survival
across multiple tumor types, particularly in melanoma. Interestingly, sex-specific differences …