La enseñanza de la investigación debe abarcar todos los aspectos de su proceso,
involucrando los estudios piloto. En la investigación biomédica, el primer paso en la …

A pilot study asks whether something can be done, should the researchers proceed with it,
and if so, how. However, a pilot study also has a specific design feature; it is conducted on a …

Recent studies in both mice and humans have suggested that gut microbiota could
modulate tumor responsiveness to chemo-or immunotherapies. However, the underlying …

Background Implementation trials aim to test the effects of implementation strategies on the
adoption, integration or uptake of an evidence-based intervention within organisations or …

As the number of submissions to Pilot and Feasibility Studies increases, there is a need for
good quality reporting guidelines to help researchers tailor their reports in a way that is …

The Consolidated Standards of Reporting Trials (CONSORT) statement is a guideline
designed to improve the transparency and quality of the reporting of randomised controlled …

We describe a framework for defining pilot and feasibility studies focusing on studies
conducted in preparation for a randomised controlled trial. To develop the framework, we …

Background The current CONSORT guidelines for reporting pilot trials do not recommend
hypothesis testing of clinical outcomes on the basis that a pilot trial is under-powered to …

Sample size justification is an important consideration when planning a clinical trial, not only
for the main trial but also for any preliminary pilot trial. When the outcome is a continuous …

Background Pilot feasibility studies serve a uniquely important role in preparing for larger
scale intervention trials by examining the feasibility and acceptability of interventions and the …