Triple-negative breast cancer (TNBC), a highly aggressive subtype of breast cancer,
negatively expresses estrogen receptor, progesterone receptor, and the human epidermal …

Cytokines are critical in regulating immune responses and cellular behavior, playing dual
roles in both normal physiology and the pathology of diseases such as cancer. These …

Epidermal growth factor receptor (EGFR), the receptor for members of the epidermal growth
factor family, regulates cell proliferation and signal transduction; moreover, EGFR is related …

Lenvatinib is an inhibitor of multiple receptor tyrosine kinases that was recently authorized
for first-line treatment of hepatocellular carcinoma (HCC). However, the clinical benefits …

Breast cancer (BC) is the most prevalent type of cancer in the world and the main reason
women die from cancer. Due to the significant side effects of conventional treatments such …

Over a century of scientific inquiry since the discovery of v-SRC but still no final judgement
on SRC function. However, a significant body of work has defined Src family kinases as key …

To uncover molecular changes underlying blood-brain-barrier dysfunction in Alzheimer's
disease, we performed single nucleus RNA sequencing in 24 Alzheimer's disease and …

Background Osteosarcoma is a common primary malignant tumour of the bone that usually
occurs in children and adolescents. It is characterised by difficult treatment, recurrence and …

In this article we review the cellular and molecular mechanisms of gastric ulcer healing. A
gastric ulcer (GU) is a deep defect in the gastric wall penetrating through the entire mucosa …

Epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) is currently the
standard first-line therapy for EGFR-mutated advanced non-small cell lung cancer (NSCLC) …