Inflammation during fetal and neonatal life: implications for neurologic and neuropsychiatric disease in children and adults
Inflammation is increasingly recognized as being of both physiological and pathological
importance in the immature brain. The rationale of this review is to present an update on this …
importance in the immature brain. The rationale of this review is to present an update on this …
The neuropathology of schizophrenia: a critical review of the data and their interpretation
PJ Harrison - Brain, 1999 - academic.oup.com
Despite a hundred years' research, the neuropathology of schizophrenia remains obscure.
However, neither can the null hypothesis be sustained—that it is afunctional'psychosis, a …
However, neither can the null hypothesis be sustained—that it is afunctional'psychosis, a …
Schizophrenia as a disorder of neurodevelopment
▪ Abstract A combination of genetic susceptibility and environmental perturbations appear to
be necessary for the expression of schizophrenia. In addition, the pathogenesis of the …
be necessary for the expression of schizophrenia. In addition, the pathogenesis of the …
Sex differences in schizophrenia, a review of the literature
DA Leung MD… - Acta Psychiatrica …, 2000 - Wiley Online Library
Objective: To comprehensively and critically review the literature on gender differences in
schizophrenia. Method: An initial search of MEDLINE abstracts (1966–1999) was conducted …
schizophrenia. Method: An initial search of MEDLINE abstracts (1966–1999) was conducted …
Stress-reactivity in psychosis: evidence for an affective pathway to psychosis
This paper will review a series of studies using the Experience Sampling Method that
suggest that altered sensitivity to stress is an endophenotype for psychosis. The Experience …
suggest that altered sensitivity to stress is an endophenotype for psychosis. The Experience …
Early detection and preventive intervention in schizophrenia: from fantasy to reality
Scientific progress in understanding human disease can be measured by the effectiveness
of its treatment. Antipsychotic drugs have been proven to alleviate acute psychotic symptoms …
of its treatment. Antipsychotic drugs have been proven to alleviate acute psychotic symptoms …
The time of prenatal immune challenge determines the specificity of inflammation-mediated brain and behavioral pathology
U Meyer, M Nyffeler, A Engler, A Urwyler… - Journal of …, 2006 - Soc Neuroscience
Disturbance to early brain development is implicated in several neuropsychiatric disorders
including autism, schizophrenia, and mental retardation. Epidemiological studies have …
including autism, schizophrenia, and mental retardation. Epidemiological studies have …
The role of the cerebellum in schizophrenia
NC Andreasen, R Pierson - Biological psychiatry, 2008 - Elsevier
For many years the cerebellum has been considered to serve as a coordinator of motor
function. Likewise, for many years schizophrenia has been considered to be a disease that …
function. Likewise, for many years schizophrenia has been considered to be a disease that …
[HTML][HTML] Increased l1 retrotransposition in the neuronal genome in schizophrenia
Recent studies indicate that long interspersed nuclear element-1 (L1) are mobilized in the
genome of human neural progenitor cells and enhanced in Rett syndrome and ataxia …
genome of human neural progenitor cells and enhanced in Rett syndrome and ataxia …
[HTML][HTML] A quantitative meta-analysis of population-based studies of premorbid intelligence and schizophrenia
OBJECTIVE: A premorbid IQ deficit supports a developmental dimension to schizophrenia
and its cognitive aspects that are crucial to functional outcome. Better characterisation of the …
and its cognitive aspects that are crucial to functional outcome. Better characterisation of the …