Colorectal cancer: Metastases to a single organ

S Vatandoust, TJ Price… - World journal of …, 2015 - pmc.ncbi.nlm.nih.gov
Colorectal cancer (CRC) is a common malignancy worldwide. In CRC patients, metastases
are the main cause of cancer-related mortality. In a group of metastatic CRC patients, the …

Management of colorectal cancer presenting with synchronous liver metastases

AK Siriwardena, JM Mason, S Mullamitha… - Nature reviews Clinical …, 2014 - nature.com
Up to a fifth of patients with colorectal cancer (CRC) present with synchronous hepatic
metastases. In patients with CRC who present without intestinal obstruction or perforation …

Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma

LJ Schouten, J Rutten, HAM Huveneers, A Twijnstra - Cancer, 2002 - Wiley Online Library
BACKGROUND The objective of this study was to report on the incidence of and factors
related to the occurrence of central nervous system metastases in a cohort of patients who …

KRAS Mutation Is Associated with Lung Metastasis in Patients with Curatively Resected Colorectal Cancer

J Tie, L Lipton, J Desai, P Gibbs… - Clinical Cancer …, 2011 - aacrjournals.org
Purpose: Oncogene mutations contribute to colorectal cancer development. We searched for
differences in oncogene mutation profiles between colorectal cancer metastases from …

Gastrointestinal cancer and brain metastasis: a rare and ominous sign

PH Go, Z Klaassen, MC Meadows, RS Chamberlain - Cancer, 2011 - Wiley Online Library
Metastatic brain tumors represent 20% to 40% of all intracranial neoplasms and are found
most frequently in association with lung cancer (50%) and breast cancer (12%). Although …

Systematic review: brain metastases from colorectal cancer—incidence and patient characteristics

TD Christensen, KLG Spindler, JA Palshof, DL Nielsen - BMC cancer, 2016 - Springer
Background Brain metastases (BM) from colorectal cancer (CRC) are a rare event. However,
the implications for affected patients are severe, and the incidence has been reported to be …

Brain metastases from colorectal cancer: risk factors, incidence, and the possible role of chemokines

JP Mongan, CE Fadul, BF Cole, BI Zaki… - Clinical colorectal …, 2009 - Elsevier
Background Brain metastases from colorectal cancer (CRC) are uncommon. There has
been relatively little published on the host and tumor factors that might lead to this clinical …

Resection of brain metastases from colorectal carcinoma in 73 patients

M Wroński, E Arbit - … Journal of the American Cancer Society, 1999 - Wiley Online Library
BACKGROUND At the time of diagnosis of colorectal carcinoma, 2–3% of patients are likely
to be harboring brain metastases, and another 10% of patients will develop brain lesions …

Clinical features and course of brain metastases in colorectal cancer: an experience from a single institution

K Damiens, JPM Ayoub, B Lemieux, F Aubin… - Current …, 2012 - pmc.ncbi.nlm.nih.gov
Objectives Brain metastases from colorectal cancer (crc) are quite rare. Here, we review the
characteristics, presentation, and clinical course of such patients at our institution. Methods …

Where are we now and where might we be headed in understanding and managing brain metastases in colorectal cancer patients?

RB Mjahed, C Astaras, A Roth, T Koessler - Current treatment options in …, 2022 - Springer
Opinion statement Compared to liver and lung metastases, brain metastases (BMs) from
colorectal cancer (CRC) are rare and remain poorly investigated despite the anticipated rise …