Amyotrophic lateral sclerosis (ALS) is the most common motor neuron degenerative disease
in adults and has also been proven to be a type of conformational disease associated with …

Simulation is a key tool in population genetics for both methods development and empirical
research, but producing simulations that recapitulate the main features of genomic datasets …

Technological development has paved the way for accelerated genomic discovery and is
bringing precision medicine into view. The goal of precision medicine is to deliver optimally …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease causing patients to
quickly lose motor neurons. The disease is characterized by a fast functional impairment and …

Compared to sites in protein-coding sequences many more targets undergoing adenosine
to inosine (A-to-I) RNA editing were discovered in non-coding regions of human cerebral …

Background Amyotrophic lateral sclerosis (ALS) is a lethal neurodegenerative disease with
death on average within 2–3 years of symptom onset. Mutations in superoxide dismutase 1 …

Introduction The process of chemical risk assessment traditionally relies on animal
experiments and associated default uncertainty factors to account for interspecies and …

BACKGROUND The most common aesthetic procedure performed worldwide is the injection
of botulinum neurotoxin Type A (BoNT-A). Aesthetic providers must fully comprehend the …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, characterized by
progressive motor neuron degeneration, muscle weakness, paralysis, and ultimately death …

Amyotrophic lateral sclerosis (ALS) is a severe disease causing motor neuron death, but a
complete cure has not been developed and related genes have not been defined in more …