The Y‐box binding protein 1 (YB‐1, YBX1) is a member of the family of DNA‐and RNA‐
binding proteins with an evolutionarily ancient and conserved cold shock domain. It falls into …

This review describes the structure and functions of Y-box binding protein 1 (YB-1) and its
homologs. Interactions of YB-1 with DNA, mRNAs, and proteins are considered. Data on the …

Akt/PKB is a serine/threonine kinase that promotes tumor cell growth by phosphorylating
transcription factors and cell cycle proteins. There is particular interest in finding tumor …

Hanahan and Weinberg have proposed the 'hallmarks of cancer'to cover the biological
changes required for the development and persistence of tumours [Hanahan and Weinberg …

Abstract p53 is the most commonly mutated gene in human cancer. After activation by
cellular stresses such as DNA damage or oncogene activation, p53, a sequence-specific …

Y box binding protein 1 (YB-1) is a protein with a highly conserved cold shock domain (CSD)
that also belongs to the family of DNA-and RNA-binding proteins. YB-1 is present in both the …

Glioma stem cells (GSCs) are the important cause of tumorigenesis, recurrence, and chemo
(radio) resistance in glioma. Targeting GSCs helps improve the outcomes of glioma …

Fibrillarin (FBL) is a highly conserved nucleolar methyltransferase responsible for
methylation of ribosomal RNA and proteins. Here, we reveal a role for FBL in DNA damage …

The 21st century will undoubtedly witness unprecedented advances in understanding the
mechanisms of the human body and in develo** biotechnology. With the map** of the …

Y-box binding protein 1 (YBX1), a member of the Cold Shock Domain protein family, is
overexpressed in various human cancers and is recognized as an oncogenic gene …