PTEN is a phosphatase which metabolises PIP 3, the lipid product of PI 3-Kinase, directly
opposing the activation of the oncogenic PI3K/AKT/mTOR signalling network. Accordingly …

MicroRNAs (miRNAs) are small non-coding RNAs regulating the expression of several
target genes. miRNAs play a significant role in cancer biology, as they can downregulate …

Identifying putative biomarkers of clinical outcomes in cancer is crucial for successful
enrichment, and for the selection of patients who are the most likely to benefit from a specific …

Abstract MicroRNA-21 (miR-21) was recognized as a key figure in the intricate web of tumor
biology, with a prominent role in regulating the PTEN tumor suppressor gene and the …

Cadmium (Cd) contamination in soils is of great concern for plant growth and human health.
Willow (Salix spp.) is a promising phytoextractor because of its high biomass production …

Aberrant microRNA (miR) expression is implicated in multiple human malignancies. miR‐21,
acting as a proto‐oncogene, is involved in a variety of cellular processes and tumorigenesis …

Purpose MicroRNAs (miRNAs) participate in a variety of biological processes, including
tumorigenesis, progression, invasion, and drug resistance to multiple cancers. Phosphatase …

Abstract Background Single nucleotide polymorphisms (SNPs) in microRNA (miRNA) genes
could alter miRNA expression levels or processing and, thus, may contribute to colorectal …

Phosphatase and tensin homolog (PTEN) is a tumour suppressor that represents one of the
most common targets for genetic defect in human cancer. PTEN controls an array of …

Reports on the correlation between the expression of Survivin/phosphatase and tensin
homolog (PTEN) proteins and clinical factors in gastric cancer (GC) are varied, and the …