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miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …
regulating mRNA through its degradation and adjusting protein levels. In recent years …
Circulating microRNAs as potential cancer biomarkers: the advantage and disadvantage
MicroRNAs are endogenous single-stranded non-coding small RNA molecules that can be
secreted into the circulation and exist stably. They usually exhibit aberrant expression under …
secreted into the circulation and exist stably. They usually exhibit aberrant expression under …
MicroRNA in lung cancer: role, mechanisms, pathways and therapeutic relevance
Lung cancer is the cardinal cause of cancer-related deaths with restricted recourse of
therapy throughout the world. Clinical success of therapies is not very promising due to-late …
therapy throughout the world. Clinical success of therapies is not very promising due to-late …
Potential clinical utility of liquid biopsy in early-stage non-small cell lung cancer
H Shen, Y **, H Zhao, M Wu, K Zhang, Z Wei, X Wang… - BMC medicine, 2022 - Springer
Background Liquid biopsy has been widely researched for early diagnosis, prognostication
and disease monitoring in lung cancer, but there is a need to investigate its clinical utility for …
and disease monitoring in lung cancer, but there is a need to investigate its clinical utility for …
Microfluidics for detection of exosomes and microRNAs in cancer: State of the art
Exosomes are small extracellular vesicles with sizes ranging from 30–150 nanometers that
contain proteins, lipids, mRNAs, microRNAs, and double-stranded DNA derived from the …
contain proteins, lipids, mRNAs, microRNAs, and double-stranded DNA derived from the …
Recent advances on high-efficiency of microRNAs in different types of lung cancer: a comprehensive review
Carcinoma of the lung is among the most common types of cancer globally. Concerning its
histology, it is categorized as a non-small cell carcinoma (NSCLC) and a small cell cancer …
histology, it is categorized as a non-small cell carcinoma (NSCLC) and a small cell cancer …
[HTML][HTML] Cancer epigenetic biomarkers in liquid biopsy for high incidence malignancies
C Palanca-Ballester, A Rodriguez-Casanova, S Torres… - Cancers, 2021 - mdpi.com
Simple Summary Apart from genetic changes, cancer is characterized by epigenetic
alterations, which indicate modifications in the DNA (such as DNA methylation) and histones …
alterations, which indicate modifications in the DNA (such as DNA methylation) and histones …
MiR-3662 suppresses hepatocellular carcinoma growth through inhibition of HIF-1α-mediated Warburg effect
Z Chen, X Zuo, Y Zhang, G Han, L Zhang, J Wu… - Cell death & …, 2018 - nature.com
Glucose metabolic reprogramming from oxidative to aerobic glycolysis, referred as the
Warburg effect, is a hallmark of tumor cells. Accumulating evidence suggests that a subset of …
Warburg effect, is a hallmark of tumor cells. Accumulating evidence suggests that a subset of …
[HTML][HTML] MicroRNA as a novel biomarker in the diagnosis of head and neck cancer
J Kabzinski, M Maczynska, I Majsterek - Biomolecules, 2021 - mdpi.com
Head and neck squamous cell carcinoma is the sixth most common cancer worldwide, with
890,000 new cases and 450,000 deaths in 2018, and although the survival statistics for …
890,000 new cases and 450,000 deaths in 2018, and although the survival statistics for …
[HTML][HTML] Circulating miRNAs as diagnostic and prognostic biomarkers in common solid tumors: focus on lung, breast, prostate cancers, and osteosarcoma
An early cancer diagnosis is essential to treat and manage patients, but it is difficult to
achieve this goal due to the still too low specificity and sensitivity of classical methods …
achieve this goal due to the still too low specificity and sensitivity of classical methods …