Rhythms of life: circadian disruption and brain disorders across the lifespan

RW Logan, CA McClung - Nature Reviews Neuroscience, 2019‏ - nature.com
Many processes in the human body—including brain function—are regulated over the 24-
hour cycle, and there are strong associations between disrupted circadian rhythms (for …

Surface modification of water purification membranes

DJ Miller, DR Dreyer, CW Bielawski… - Angewandte Chemie …, 2017‏ - Wiley Online Library
Polymeric membranes are an energy‐efficient means of purifying water, but they suffer from
fouling during filtration. Modification of the membrane surface is one route to mitigating …

Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease

FA Zucca, J Segura-Aguilar, E Ferrari, P Muñoz… - Progress in …, 2017‏ - Elsevier
There are several interrelated mechanisms involving iron, dopamine, and neuromelanin in
neurons. Neuromelanin accumulates during aging and is the catecholamine-derived …

Oxidative stress and cellular pathologies in Parkinson's disease

L Puspita, SY Chung, J Shim - Molecular brain, 2017‏ - Springer
Parkinson's disease (PD) is a chronic and progressive neurodegeneration of dopamine
neurons in the substantia nigra. The reason for the death of these neurons is unclear; …

Melanins and melanogenesis: from pigment cells to human health and technological applications

M d'Ischia, K Wakamatsu, F Cicoira… - Pigment cell & …, 2015‏ - Wiley Online Library
During the past decade, melanins and melanogenesis have attracted growing interest for a
broad range of biomedical and technological applications. The burst of polydopamine …

Differential pulse voltammetry and chronoamperometry as analytical tools for epinephrine detection using a tyrosinase-based electrochemical biosensor

S Baluta, F Meloni, K Halicka, A Szyszka, A Zucca… - RSC …, 2022‏ - pubs.rsc.org
The main goal of the presented study was to design a biosensor-based system for
epinephrine (EP) detection using a poly-thiophene derivative and tyrosinase as a …

Elucidating the structure of poly (dopamine)

DR Dreyer, DJ Miller, BD Freeman, DR Paul… - Langmuir, 2012‏ - ACS Publications
Herein we propose a new structure for poly (dopamine), a synthetic eumelanin that has
found broad utility as an antifouling agent. Commercially available 3-hydroxytyramine …

Dopamine, oxidative stress and protein–quinone modifications in Parkinson's and other neurodegenerative diseases

E Monzani, S Nicolis, S Dell'Acqua… - Angewandte Chemie …, 2019‏ - Wiley Online Library
Dopamine (DA) is the most important catecholamine in the brain, as it is the most abundant
and the precursor of other neurotransmitters. Degeneration of nigrostriatal neurons of …

Protective and toxic roles of dopamine in Parkinson's disease

J Segura‐Aguilar, I Paris, P Muñoz… - Journal of …, 2014‏ - Wiley Online Library
The molecular mechanisms causing the loss of dopaminergic neurons containing
neuromelanin in the substantia nigra and responsible for motor symptoms of Parkinson's …

Biosensor technology: recent advances in threat agent detection and medicine

J Kirsch, C Siltanen, Q Zhou, A Revzin… - Chemical Society …, 2013‏ - pubs.rsc.org
Biosensors are of great significance because of their capability to resolve a potentially large
number of analytical problems and challenges in very diverse areas such as defense …