Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
[HTML][HTML] Effects of hydrogen sulfide on mitochondrial function and cellular bioenergetics
Hydrogen sulfide (H 2 S) was once considered to have only toxic properties, until it was
discovered to be an endogenous signaling molecule. The effects of H 2 S are dose …
discovered to be an endogenous signaling molecule. The effects of H 2 S are dose …
Cystathionine-β-synthase: molecular regulation and pharmacological inhibition
Cystathionine-β-synthase (CBS), the first (and rate-limiting) enzyme in the transsulfuration
pathway, is an important mammalian enzyme in health and disease. Its biochemical …
pathway, is an important mammalian enzyme in health and disease. Its biochemical …
Protein S-sulfhydration: unraveling the prospective of hydrogen sulfide in the brain, vasculature and neurological manifestations
Hydrogen sulfide (H 2 S) and hydrogen polysulfides (H 2 S n) are essential regulatory
signaling molecules generated by the entire body, including the central nervous system …
signaling molecules generated by the entire body, including the central nervous system …
Advances of H2S in Regulating Neurodegenerative Diseases by Preserving Mitochondria Function
L Zhou, Q Wang - Antioxidants, 2023 - mdpi.com
Neurotoxicity is induced by different toxic substances, including environmental chemicals,
drugs, and pathogenic toxins, resulting in oxidative damage and neurodegeneration in …
drugs, and pathogenic toxins, resulting in oxidative damage and neurodegeneration in …
Role of hydrogen sulfide and polysulfides in neurological diseases: focus on protein S-persulfidation
Hydrogen sulfide (H2S) and hydrogen polysulfides are recognized as important signaling
molecules that are generated physiologically in the body, including the central nervous …
molecules that are generated physiologically in the body, including the central nervous …
Hydrogen sulfide signalling in neurodegenerative diseases
The gaseous neurotransmitter hydrogen sulfide (H2S) exerts neuroprotective efficacy in the
brain via post‐translational modification of cysteine residues by sulfhydration, also known as …
brain via post‐translational modification of cysteine residues by sulfhydration, also known as …
Physiological functions and donor design of hydrogen sulfide and its application in central nervous system diseases
Z Zhao, W Guo, C Xu, Q Wang, C Mao… - Chemical Engineering …, 2023 - Elsevier
In the past decades, hydrogen sulfide (H 2 S) has been considered as an important signal
molecule with a wide range of physiological functions. Therefore, disease treatment …
molecule with a wide range of physiological functions. Therefore, disease treatment …
[HTML][HTML] Oxidative cysteine post translational modifications drive the redox code underlying neurodegeneration and amyotrophic lateral sclerosis
A Percio, M Cicchinelli, D Masci, M Summo, A Urbani… - Antioxidants, 2024 - mdpi.com
Redox dysregulation, an imbalance between oxidants and antioxidants, is crucial in the
pathogenesis of various neurodegenerative diseases. Within this context, the “redoxome” …
pathogenesis of various neurodegenerative diseases. Within this context, the “redoxome” …
[HTML][HTML] Tyzzerella nexilis strains enriched in mobile genetic elements are involved in progressive multiple sclerosis
Multiple sclerosis (MS) is an autoimmune-demyelinating disease with an inflammatory
pathology formed by self-reactive lymphocytes with activated glial cells. Progressive MS …
pathology formed by self-reactive lymphocytes with activated glial cells. Progressive MS …