Target trial emulation has drastically improved the quality of observational studies
investigating the effects of interventions. Its ability to prevent avoidable biases that have …

An increasing number of patients waitlisted for kidney transplantation have a previously
failed graft. Retransplantation provides a significant improvement in morbidity, mortality, and …

Rationale & Objective Despite a lack of supporting evidence, current guidance recommends
against the use of metformin in people with advanced kidney impairment. This observational …

Kidney transplantation (KT) is recognized as the gold-standard of treatment for patients with
end-stage renal disease. Additionally, it has been demonstrated that receiving a pre-emptive …

Conservative kidney management (CKM) has been increasingly accepted as a therapeutic
option for seriously ill patients with advanced chronic kidney disease. CKM is active medical …

Aneurysms remain the most common complication of an arteriovenous fistula created for
dialysis access. The management of an aneurysmal arteriovenous fistula (AAVF) in kidney …

Background There is a lack of information regarding which is the best dialysis technique
after kidney transplant (KT) failure. The aim of this study is to compare the effect of kidney …

The management of failing kidney allograft and transition of care to general nephrologists
(GN) remain a complex process. The Kidney Pancreas Community of Practice (KPCOP) …

Background Following kidney transplant failure, patients generally have three kidney
replacement therapy (KRT) options: peritoneal dialysis (PD), haemodialysis (HD), or pre …

Introduction Prolonged immunosuppression after dialysis start has been assumed to reduce
sensitization, need for graft nephrectomy, and to favor re-transplantation. In contrast …