Infectious keratitis: A review

M Cabrera‐Aguas, P Khoo… - Clinical & Experimental …, 2022 - Wiley Online Library
Globally, infectious keratitis is the fifth leading cause of blindness. The main predisposing
factors include contact lens wear, ocular injury and ocular surface disease. Staphylococcus …

Foundational concepts in the biology of bacterial keratitis

L Ung, J Chodosh - Experimental eye research, 2021 - Elsevier
Bacterial infections of the cornea, or bacterial keratitis (BK), are notorious for causing rapidly
fulminant disease and permanent vision loss, even among treated patients. In the last sixty …

An injectable, shape-retaining collagen hydrogel cross-linked using thiol-maleimide click chemistry for sealing corneal perforations

J Rosenquist, M Folkesson, L Höglund… - … Applied Materials & …, 2023 - ACS Publications
Injectable hydrogels show great promise in develo** novel regenerative medicine
solutions and present advantages for minimally invasive applications. Hydrogels based on …

In situ-forming collagen hydrogel crosslinked via multi-functional PEG as a matrix therapy for corneal defects

GM Fernandes-Cunha, KM Chen, F Chen, P Le… - Scientific reports, 2020 - nature.com
Visually significant corneal injuries and subsequent scarring collectively represent a major
global human health challenge, affecting millions of people worldwide. Unfortunately, less …

Paradox of complex diversity: Challenges in the diagnosis and management of bacterial keratitis

RB Singh, S Das, J Chodosh, N Sharma… - Progress in Retinal and …, 2022 - Elsevier
Bacterial keratitis continues to be one of the leading causes of corneal blindness in the
developed as well as the develo** world, despite swift progress since the dawn of the …

Ciprofloxacin-loaded bioadhesive hydrogels for ocular applications

IA Khalil, B Saleh, DM Ibrahim, C Jumelle, A Yung… - Biomaterials …, 2020 - pubs.rsc.org
The management of corneal infections often requires complex therapeutic regimens
involving the prolonged and high-frequency application of antibiotics that provide many …

Development and characterization of a hydrogel-based adhesive patch for sealing open-globe injuries

C Jumelle, A Yung, ES Sani, Y Taketani, F Gantin… - Acta biomaterialia, 2022 - Elsevier
Full-thickness wounds to the eye can lead to serious vision impairment. Current standards of
care (from suturing to tissue transplantation) usually require highly skilled surgeons and use …

[HTML][HTML] Human cornea-derived extracellular matrix hydrogel for prevention of post-traumatic corneal scarring: A translational approach

S Chameettachal, A Venuganti, Y Parekh, D Prasad… - Acta Biomaterialia, 2023 - Elsevier
Corneal scarring and opacification are a significant cause of blindness affecting millions
worldwide. The current standard of care for corneal blindness is corneal transplantation …

Decellularized porcine cornea-derived hydrogels for the regeneration of epithelium and stroma in focal corneal defects

F Wang, W Shi, H Li, H Wang, D Sun, L Zhao, L Yang… - The ocular …, 2020 - Elsevier
Purpose Hydrogels derived from decellularized tissues provide superior biocompatibility,
tenability and tissue-specific extracellular matrix (ECM) components. Based on the …

Tissue adhesives for the management of corneal perforations and challenging corneal conditions

A Sharma, N Sharma, S Basu, R Sharma… - Clinical …, 2023 - Taylor & Francis
Corneal perforations are ophthalmological emergencies which can have serious and
detrimental consequences, if not managed timely and appropriately. These are a significant …