Identification of intrinsic brain activity differences and similarities between major depression
(MDD) and bipolar disorder (BD) is necessary. However, results have not yet yielded …

The so-called resting state, in which participants lie quietly with no particular inputs or
outputs, represented a paradigm shift from conventional task-based studies in human …

Background Suicide is a leading cause of death in persons with schizophrenia and other
serious mental illnesses (SMI), however, little is known about the characteristics and …

Rapid-acting interventions for the suicide crisis have the potential to transform treatment. In
addition, recent innovations in suicide research methods may similarly expand our …

Whether remitted major depressive disorder (rMDD) and MDD present common or distinct
neuropathological mechanisms remains unclear. We performed a meta-analysis of task …

Background Altered structural and functional brain networks have been extensively studied
in major depressive disorder (MDD) patients. However, whether the differential connectivity …

Context Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, has been shown to
exhibit anti-depressive effects in clinical trials. However, the direct mechanism underlying its …

Childhood maltreatment (CM) is regarded as an important risk factor for major depressive
disorder (MDD). However, the neural links corresponding to the process of early CM …

Brain targets to lower the high risk of suicide in Bipolar Disorder (BD) are needed.
Neuroimaging studies employing analyses dependent on regional assumptions could miss …

Although suicide risk is a major public health issue, attempts to understand the neural basis
of suicidality have been limited by small sample sizes and a focus on specific psychiatric …