Breast cancer is one of the leading causes of mortality in the females. Intensive efforts have
been made to understand the molecular mechanisms of pathogenesis of breast cancer. The …

Cytokines are low molecular weight regulatory proteins or glycoprotein that modulates the
intensity and duration of immune response by stimulating or inhibiting the activation …

Background: Interleukin (IL)-10, a multifunctional immune-regulatory cytokine with both
immunosuppressive and anti-angiogenic functions, is produced by immune cells including …

Metastasis is a critical event affecting breast cancer patient survival. To identify molecules
contributing to the metastatic process, we analysed The Cancer Genome Atlas (TCGA) …

Decades of research are now leading to therapeutics that target the molecular mechanisms
of the cancer-specific immune response. These therapeutics include tumor antigen …

Purpose To evaluate the effect of esketamine combined with ultrasound-guided pectoral
nerve block type II (Pecs II block) on the quality of early postoperative recovery in patients …

The identification of tumor-specific antigens and the immune responses directed against
them has instigated the development of therapies to enhance antitumor immune responses …

IFNB1/interferon (IFN)-β belongs to the type I IFNs and exerts potent antiproliferative,
proapoptotic, antiangiogenic and immunemodulatory functions. Despite the beneficial …

Surgery is the first-line treatment for early, localized, or operable breast cancer. Regional
anesthesia during mastectomy may offer the prevention of postoperative pain. One potential …

This study aimed to explore the role of a stimulator of interferon (IFN) gene (STING) agonist
in breast cancer (BCa) immunotherapy. Clinical samples were collected from 37 patients …