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Once and only once: mechanisms of centriole duplication and their deregulation in disease
EA Nigg, AJ Holland - Nature reviews Molecular cell biology, 2018 - nature.com
Centrioles are conserved microtubule-based organelles that form the core of the centrosome
and act as templates for the formation of cilia and flagella. Centrioles have important roles in …
and act as templates for the formation of cilia and flagella. Centrioles have important roles in …
Mechanism and regulation of centriole and cilium biogenesis
DK Breslow, AJ Holland - Annual review of biochemistry, 2019 - annualreviews.org
The centriole is an ancient microtubule-based organelle with a conserved nine-fold
symmetry. Centrioles form the core of centrosomes, which organize the interphase …
symmetry. Centrioles form the core of centrosomes, which organize the interphase …
[HTML][HTML] Human iPSC-derived cerebral organoids model cellular features of lissencephaly and reveal prolonged mitosis of outer radial glia
M Bershteyn, TJ Nowakowski, AA Pollen, E Di Lullo… - Cell stem cell, 2017 - cell.com
Classical lissencephaly is a genetic neurological disorder associated with mental
retardation and intractable epilepsy, and Miller-Dieker syndrome (MDS) is the most severe …
retardation and intractable epilepsy, and Miller-Dieker syndrome (MDS) is the most severe …
FMRP modulates neural differentiation through m6A-dependent mRNA nuclear export
Summary N 6-methyladenosine (m 6 A) modification of mRNA is emerging as a vital
mechanism regulating RNA function. Here, we show that fragile X mental retardation protein …
mechanism regulating RNA function. Here, we show that fragile X mental retardation protein …
Spindle positioning and its impact on vertebrate tissue architecture and cell fate
T Lechler, M Mapelli - Nature Reviews Molecular Cell Biology, 2021 - nature.com
In multicellular systems, oriented cell divisions are essential for morphogenesis and
homeostasis as they determine the position of daughter cells within the tissue and also, in …
homeostasis as they determine the position of daughter cells within the tissue and also, in …
[HTML][HTML] Zika virus infects neural progenitors in the adult mouse brain and alters proliferation
Zika virus (ZIKV)-related neuropathology is an important global health concern. Several
studies have shown that ZIKV can infect neural stem cells in the develo** brain, but …
studies have shown that ZIKV can infect neural stem cells in the develo** brain, but …
Differences and similarities between human and chimpanzee neural progenitors during cerebral cortex development
F Mora-Bermúdez, F Badsha, S Kanton, JG Camp… - Elife, 2016 - elifesciences.org
Human neocortex expansion likely contributed to the remarkable cognitive abilities of
humans. This expansion is thought to primarily reflect differences in proliferation versus …
humans. This expansion is thought to primarily reflect differences in proliferation versus …
Making Ramón y Cajal proud: Development of cell identity and diversity in the cerebral cortex
DJ Di Bella, N Domínguez-Iturza, JR Brown, P Arlotta - Neuron, 2024 - cell.com
Since the beautiful images of Santiago Ramón y Cajal provided a first glimpse into the
immense diversity and complexity of cell types found in the cerebral cortex, neuroscience …
immense diversity and complexity of cell types found in the cerebral cortex, neuroscience …
Cellular and molecular mechanisms linking human cortical development and evolution
B Libé-Philippot, P Vanderhaeghen - Annual review of genetics, 2021 - annualreviews.org
The cerebral cortex is at the core of brain functions that are thought to be particularly
developed in the human species. Human cortex specificities stem from divergent features of …
developed in the human species. Human cortex specificities stem from divergent features of …
Map** the molecular and cellular complexity of cortical malformations
INTRODUCTION The cerebral cortex, or neocortex, is critical to key mammalian skills such
as language, sociability, and sensorimotor control. This structure consists of dozens of …
as language, sociability, and sensorimotor control. This structure consists of dozens of …