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A census of human RNA-binding proteins
Post-transcriptional gene regulation (PTGR) concerns processes involved in the maturation,
transport, stability and translation of coding and non-coding RNAs. RNA-binding proteins …
transport, stability and translation of coding and non-coding RNAs. RNA-binding proteins …
RNA–protein interactions: disorder, moonlighting and junk contribute to eukaryotic complexity
RNA–protein interactions are crucial for most biological processes in all organisms.
However, it appears that the complexity of RNA-based regulation increases with the …
However, it appears that the complexity of RNA-based regulation increases with the …
Exosomal circLPAR1 functions in colorectal cancer diagnosis and tumorigenesis through suppressing BRD4 via METTL3–eIF3h interaction
R Zheng, K Zhang, S Tan, F Gao, Y Zhang, W Xu… - Molecular cancer, 2022 - Springer
Background Exosomes have emerged as vital biomarkers of multiple cancers and contain
abundant circular RNAs (circRNAs). However, the potential for exosomal circRNAs to be …
abundant circular RNAs (circRNAs). However, the potential for exosomal circRNAs to be …
RNA structure drives interaction with proteins
N Sanchez de Groot, A Armaos… - Nature …, 2019 - nature.com
The combination of high-throughput sequencing and in vivo crosslinking approaches leads
to the progressive uncovering of the complex interdependence between cellular …
to the progressive uncovering of the complex interdependence between cellular …
catRAPID omics v2.0: going deeper and wider in the prediction of protein–RNA interactions
Prediction of protein–RNA interactions is important to understand post-transcriptional events
taking place in the cell. Here we introduce cat RAPID omics v2. 0, an update of our web …
taking place in the cell. Here we introduce cat RAPID omics v2. 0, an update of our web …
Advances in the characterization of RNA‐binding proteins
D Marchese, NS de Groot… - Wiley …, 2016 - Wiley Online Library
From transcription, to transport, storage, and translation, RNA depends on association with
different RNA‐binding proteins (RBPs). Methods based on next‐generation sequencing and …
different RNA‐binding proteins (RBPs). Methods based on next‐generation sequencing and …
RNA-binding and prion domains: the Yin and Yang of phase separation
NL Gotor, A Armaos, G Calloni… - Nucleic acids …, 2020 - academic.oup.com
Proteins and RNAs assemble in membrane-less organelles that organize intracellular
spaces and regulate biochemical reactions. The ability of proteins and RNAs to form …
spaces and regulate biochemical reactions. The ability of proteins and RNAs to form …
Discovering the 3′ UTR-mediated regulation of alpha-synuclein
Recent evidence indicates a link between Parkinson's Disease (PD) and the expression of a-
synuclein (SNCA) isoforms with different 3′ untranslated regions (3′ UTRs). Yet, the post …
synuclein (SNCA) isoforms with different 3′ untranslated regions (3′ UTRs). Yet, the post …
The cryptic lncRNA-encoded microprotein TPM3P9 drives oncogenic RNA splicing and tumorigenesis
K Meng, Y Li, X Yuan, HM Shen, LL Hu, D Liu… - … and Targeted Therapy, 2025 - nature.com
Emerging evidence demonstrates that cryptic translation from RNAs previously annotated as
noncoding might generate microproteins with oncogenic functions. However, the importance …
noncoding might generate microproteins with oncogenic functions. However, the importance …
The cleverSuite approach for protein characterization: predictions of structural properties, solubility, chaperone requirements and RNA-binding abilities
Motivation: The recent shift towards high-throughput screening is posing new challenges for
the interpretation of experimental results. Here we propose the cleverSuite approach for …
the interpretation of experimental results. Here we propose the cleverSuite approach for …