An ATP-powered DNA translocation machine encapsidates the viral genome in the large
dsDNA bacteriophages. The essential components include the empty shell, prohead, and …

Phage λ, like a number of other large DNA bacterio‐phages and the herpesviruses,
produces concatemeric DNA during DNA replication. The concatemeric DNA is processed to …

The introduction of the use of T-even bacteriophages as genetic and biochemical
experimental systems by Max Delbriick in the late 1930s has led to the intense study of …

The mosaic composition of the genomes of dsDNA tailed bacteriophages (Caudovirales) is
well known. Observations of this mosaicism have generally come from comparisons of small …

This review focuses on the biochemical, biophysical, and catalytic properties of terminase,
an enzyme involved in bacteriophage λ genome packaging. The holoenzyme possesses …

Large dsDNA bacteriophages and herpesviruses encode a powerful ATP-driven DNA-
translocating machine that encapsidates a viral genome into a preformed capsid shell or …

The genome packaging motor of bacteriophages and herpesviruses is built by two
terminase subunits, known as large (TerL) and small (TerS), both essential for viral genome …

The viruses have been an attractive model for the study of basic mechanisms of
protein/protein and protein/nucleic acid interactions involved in the assembly of …

Tailed DNA bacteriophages assemble empty procapsids that are subsequently filled with the
viral genome by means of a DNA packaging machine situated at a special fivefold vertex …

Phage-inducible chromosomal islands (PICIs) represent a novel and universal class of
mobile genetic elements, which have broad impact on bacterial virulence. In spite of their …