Lipid hijacking: a unifying theme in vector-borne diseases

AJ O'Neal, LR Butler, A Rolandelli, SD Gilk, JHF Pedra - Elife, 2020 - elifesciences.org
Vector-borne illnesses comprise a significant portion of human maladies, representing 17%
of global infections. Transmission of vector-borne pathogens to mammals primarily occurs …

Lipid metabolism in insect disease vectors

KC Gondim, GC Atella, EG Pontes… - Insect biochemistry and …, 2018 - Elsevier
More than a third of the world population is at constant risk of contracting some insect-
transmitted disease, such as Dengue fever, Zika virus disease, malaria, Chagas' disease …

The antiviral effect of metformin on zika and dengue virus infection

CN Farfan-Morales, CD Cordero-Rivera… - Scientific Reports, 2021 - nature.com
The Dengue (DENV) and zika (ZIKV) virus infections are currently a public health concern.
At present, there is no treatment or a safe and effective vaccine for these viruses. Hence, the …

Metabolite dynamics and phytochemistry of a soy whey-based beverage bio-transformed by water kefir consortium

F Azi, C Tu, L Meng, L Zhiyu, MT Cherinet… - Food Chemistry, 2021 - Elsevier
Integrated metabolomic and metagenomic techniques were used to study the metabolite
dynamics and phytochemistry of a soy whey-based beverage bio-transformed by water kefir …

Diagnostic potential of the plasma lipidome in infectious disease: application to acute SARS-CoV-2 infection

N Gray, NG Lawler, AX Zeng, M Ryan, SH Bong… - Metabolites, 2021 - mdpi.com
Improved methods are required for investigating the systemic metabolic effects of SARS-
CoV-2 infection and patient stratification for precision treatment. We aimed to develop an …

A global lipid map defines a network essential for Zika virus replication

HC Leier, JB Weinstein, JE Kyle, JY Lee… - Nature …, 2020 - nature.com
Zika virus (ZIKV), an arbovirus of global concern, remodels intracellular membranes to form
replication sites. How ZIKV dysregulates lipid networks to allow this, and consequences for …

Zika virus infection modulates the metabolomic profile of microglial cells

F Diop, T Vial, P Ferraris, S Wichit, M Bengue… - PLoS …, 2018 - journals.plos.org
Zika virus (ZIKV) is an emerging arbovirus of the Flaviviridae family. Although infection with
ZIKV generally leads to mild disease, its recent emergence in the Americas has been …

Anti-flavivirus properties of lipid-lowering drugs

CN Farfan-Morales, CD Cordero-Rivera… - Frontiers in …, 2021 - frontiersin.org
Although Flaviviruses such as dengue (DENV) and zika (ZIKV) virus are important human
pathogens, an effective vaccine or antiviral treatment against them is not available. Hence …

Glycerophospholipid remodeling is critical for orthoflavivirus infection

J Hehner, L Schneider, A Woitalla, B Ott… - Nature …, 2024 - nature.com
Flavivirus infection is tightly connected to host lipid metabolism. Here, we performed shotgun
lipidomics of cells infected with neurotropic Zika, West Nile, and tick-borne encephalitis …

Altered lipid profile in COVID-19 patients and metabolic reprogramming

T Zhao, C Wang, B Duan, P Yang, J Wu… - Frontiers in …, 2022 - frontiersin.org
Background Coronavirus disease 2019 (COVID-19) is a global pandemic. Previous studies
have reported dyslipidemia in patients with COVID-19. Herein, we conducted a retrospective …