Diabetic nephropathy: challenges in pathogenesis, diagnosis, and treatment

N Samsu - BioMed research international, 2021 - Wiley Online Library
Diabetic nephropathy (DN) is the leading cause of end‐stage renal disease worldwide.
Chronic hyperglycemia and high blood pressure are the main risk factors for the …

Uric acid and oxidative stress—relationship with cardiovascular, metabolic, and renal impairment

ME Gherghina, I Peride, M Tiglis, TP Neagu… - International Journal of …, 2022 - mdpi.com
Background: The connection between uric acid (UA) and renal impairment is well known
due to the urate capacity to precipitate within the tubules or extra-renal system. Emerging …

[HTML][HTML] Uric acid and cardiovascular disease: a clinical review

Y Saito, A Tanaka, K Node, Y Kobayashi - Journal of cardiology, 2021 - Elsevier
Uric acid, the end-product of purine metabolism in humans, is not only a cause of gout, but
also may play roles in develo** cardiovascular diseases such as hypertension, atrial …

Cardiovascular risk in inflammatory arthritis: rheumatoid arthritis and gout

R Hansildaar, D Vedder, M Baniaamam… - The Lancet …, 2021 - thelancet.com
The increased risk of cardiovascular morbidity and mortality in rheumatoid arthritis and gout
has been increasingly acknowledged in past decades, with accumulating evidence that …

Hyperuricemia, acute and chronic kidney disease, hypertension, and cardiovascular disease: report of a scientific workshop organized by the National Kidney …

RJ Johnson, GL Bakris, C Borghi, MB Chonchol… - American Journal of …, 2018 - Elsevier
Urate is a cause of gout, kidney stones, and acute kidney injury from tumor lysis syndrome,
but its relationship to kidney disease, cardiovascular disease, and diabetes remains …

[HTML][HTML] Uric acid in the pathogenesis of metabolic, renal, and cardiovascular diseases: a review

UAAS El Din, MM Salem, DO Abdulazim - Journal of advanced research, 2017 - Elsevier
The association between uric acid (UA) on one side and systemic hypertension (Htn),
dyslipidemia, glucose intolerance, overweight, fatty liver, renal disease and cardiovascular …

Serum uric acid and the risk of cardiovascular and renal disease

C Borghi, EA Rosei, T Bardin, J Dawson… - Journal of …, 2015 - journals.lww.com
Substantial evidence suggests that chronic hyperuricemia is an independent risk factor for
hypertension, metabolic syndrome, chronic kidney disease (CKD) and cardiovascular …

Fructose consumption, lipogenesis, and non-alcoholic fatty liver disease

KW Ter Horst, MJ Serlie - Nutrients, 2017 - mdpi.com
Increased fructose consumption has been suggested to contribute to non-alcoholic fatty liver
disease (NAFLD), dyslipidemia, and insulin resistance, but a causal role of fructose in these …

Uric acid in metabolic syndrome: from an innocent bystander to a central player

M Kanbay, T Jensen, Y Solak, M Le… - European journal of …, 2016 - Elsevier
Uric acid, once viewed as an inert metabolic end-product of purine metabolism, has been
recently incriminated in a number of chronic disease states, including hypertension …

Uric acid and chronic kidney disease: which is chasing which?

RJ Johnson, T Nakagawa, D Jalal… - Nephrology Dialysis …, 2013 - academic.oup.com
Serum uric acid is commonly elevated in subjects with chronic kidney disease (CKD), but
was historically viewed as an issue of limited interest. Recently, uric acid has been …