Valvular heart disease: shifting the focus to the myocardium

N Ajmone Marsan, V Delgado, DJ Shah… - European heart …, 2023 - academic.oup.com
Adverse cardiac remodelling is the main determinant of patient prognosis in degenerative
valvular heart disease (VHD). However, to give an indication for valvular intervention …

Sex‐related differences in contemporary biomarkers for heart failure: a review

N Suthahar, LMG Meems, JE Ho… - European journal of …, 2020 - Wiley Online Library
The use of circulating biomarkers for heart failure (HF) is engrained in contemporary
cardiovascular practice and provides objective information about various pathophysiological …

Prevalence and outcome of dual aortic stenosis and cardiac amyloid pathology in patients referred for transcatheter aortic valve implantation

PR Scully, KP Patel, TA Treibel… - European heart …, 2020 - academic.oup.com
Aims Cardiac amyloidosis is common in elderly patients with aortic stenosis (AS) referred for
transcatheter aortic valve implantation (TAVI). We hypothesized that patients with dual aortic …

Early intervention in patients with asymptomatic severe aortic stenosis and myocardial fibrosis: the EVOLVED randomized clinical trial

K Loganath, NJ Craig, RJ Everett, R Bing… - JAMA, 2025 - jamanetwork.com
Importance Development of myocardial fibrosis in patients with aortic stenosis precedes left
ventricular decompensation and is associated with an adverse long-term prognosis …

Proposed stages of myocardial phenotype development in Fabry disease

S Nordin, R Kozor, K Medina-Menacho… - JACC: Cardiovascular …, 2019 - jacc.org
Objectives: This study sought to explore the Fabry myocardium in relation to storage, age,
sex, structure, function, electrocardiogram changes, blood biomarkers, and …

Sex‐and age‐based differences in the natural history and outcome of dilated cardiomyopathy

BP Halliday, A Gulati, A Ali, S Newsome… - European journal of …, 2018 - Wiley Online Library
Aim To evaluate the relationship between sex, age and outcome in dilated cardiomyopathy
(DCM). Methods and results We used proportional hazard modelling to examine the …

Sex-specific associations of cardiovascular risk factors and biomarkers with incident heart failure

N Suthahar, ES Lau, MJ Blaha, SM Paniagua… - Journal of the American …, 2020 - jacc.org
Background Whether cardiovascular (CV) disease risk factors and biomarkers associate
differentially with heart failure (HF) risk in men and women is unclear. Objectives The …

Excess mortality and undertreatment of women with severe aortic stenosis

C Tribouilloy, Y Bohbot, D Rusinaru… - Journal of the …, 2021 - ahajournals.org
Background Although women represent half of the population burden of aortic stenosis (AS),
little is known whether sex affects the presentation, management, and outcome of patients …

Sex-related differences in the extent of myocardial fibrosis in patients with aortic valve stenosis

L Tastet, J Kwiecinski, P Pibarot, R Capoulade… - Cardiovascular …, 2020 - jacc.org
Objectives The aim of this study was to assess the effect of sex on myocardial fibrosis as
assessed by using cardiac magnetic resonance (CMR) imaging in aortic stenosis (AS) …

Usefulness of cardiac magnetic resonance imaging in aortic stenosis

Y Bohbot, C Renard, A Manrique, F Levy… - Circulation …, 2020 - ahajournals.org
The objective of this review is to provide an overview of the role of cardiac magnetic
resonance (CMR) in aortic stenosis (AS). Although CMR is undeniably the gold standard for …