With new data about different aspects of schizophrenia being continually generated, it
becomes necessary to periodically revisit exactly what we know. Along with a need to review …

Schizophrenia risk has often been conceptualized using a model which requires two hits in
order to generate the clinical phenotype—the first as an early priming in a genetically …

Brain structure varies between people in a markedly organized fashion. Communities of
brain regions co-vary in their morphological properties. For example, cortical thickness in …

An interaction between external stressors and intrinsic vulnerability is one of the longest
standing pathoaetiological explanations for schizophrenia. However, novel lines of evidence …

Our ability to differentiate between simple facial expressions of emotion develops between
infancy and early adulthood, yet few studies have explored the developmental trajectory of …

Structural brain abnormalities are central to schizophrenia (SZ), but it remains unknown
whether they are linked to dysmaturational processes crossing diagnostic boundaries …

Neurocognitive deficits are evident both in established schizophrenia and bipolar disorder
(BP). However, it has been suggested that schizophrenia, but not BP, is characterized by …

Personalized medicine is rapidly becoming a reality in today's physical medicine. However,
as yet this is largely an aspirational goal in psychiatry, despite significant advances in our …

Early-life development is characterized by dramatic changes, impacting lifespan function
more than changes in any other period. Developmental origins of neurocognitive late-life …

Importance Growing evidence supports an association between attention-
deficit/hyperactivity disorder (ADHD) in childhood and subsequent psychotic disorders. Both …