Natural products from mangrove sediments-derived microbes: Structural diversity, bioactivities, biosynthesis, and total synthesis

K Li, S Chen, X Pang, J Cai, X Zhang, Y Liu… - European Journal of …, 2022 - Elsevier
The mangrove forests are a complex ecosystem, and the microbial communities in
mangrove sediments play a critical role in the biogeochemical cycles of mangrove …

[HTML][HTML] Lipopeptides development in cosmetics and pharmaceutical applications: a comprehensive review

M Pilz, P Cavelius, F Qoura, D Awad, T Brück - Biotechnology Advances, 2023 - Elsevier
Lipopeptides are surface active, natural products of bacteria, fungi and green-blue algae
origin, having diverse structures and functionalities. In analogy, a number of chemical …

Streptomyces polyketides mediate bacteria–fungi interactions across soil environments

MKC Krespach, MC Stroe, T Netzker, M Rosin… - Nature …, 2023 - nature.com
Although the interaction between prokaryotic and eukaryotic microorganisms is crucial for
the functioning of ecosystems, information about the processes driving microbial interactions …

Characterization of giant modular PKSs provides insight into genetic mechanism for structural diversification of aminopolyol polyketides

L Zhang, T Hashimoto, B Qin… - Angewandte Chemie …, 2017 - Wiley Online Library
Polyketides form many clinically valuable compounds. However, manipulation of their
biosynthesis remains highly challenging. An understanding of gene cluster evolution …

The anti-staphylococcal lipolanthines are ribosomally synthesized lipopeptides

V Wiebach, A Mainz, MAJ Siegert… - Nature chemical …, 2018 - nature.com
The potent antibacterial lanthipeptide microvionin, isolated from a culture of Microbacterium
arborescens, exhibits a new triamino-dicarboxylic acid moiety, termed avionin, and an …

The chemistry and biology of guanidine natural products

RGS Berlinck, S Romminger - Natural Product Reports, 2016 - pubs.rsc.org
Covering: 2012 to 2014. Previous review: Nat. Prod. Rep., 2012, 29, 1382 The present
review discusses the isolation, structure determination, synthesis, biosynthesis and …

Recent advances in the biosynthesis of unusual polyketide synthase substrates

L Ray, BS Moore - Natural product reports, 2016 - pubs.rsc.org
Covering: 2003 to July 2015 for polyketide synthase starter units and 2012 to September
2015 for polyketide synthase extender units This highlight provides an overview of recent …

The uncommon enzymology of cis-acyltransferase assembly lines

AT Keatinge-Clay - Chemical reviews, 2017 - ACS Publications
The enzymology of 135 assembly lines containing primarily cis-acyltransferase modules is
comprehensively analyzed, with greater attention paid to less common phenomena. Diverse …

Lichen-like association of Chlamydomonas reinhardtii and Aspergillus nidulans protects algal cells from bacteria

MKC Krespach, M García-Altares, M Flak… - The ISME …, 2020 - academic.oup.com
Organismal interactions within microbial consortia and their responses to harmful intruders
remain largely understudied. An important step toward the goal of understanding functional …

Application of an Acyl-CoA Ligase from Streptomyces aizunensis for Lactam Biosynthesis

J Zhang, JF Barajas, M Burdu, G Wang… - ACS Synthetic …, 2017 - ACS Publications
ε-Caprolactam and δ-valerolactam are important commodity chemicals used in the
manufacture of nylons, with millions of tons produced annually. Biological production of …