Potential mechanisms of bisphenol A (BPA) contributing to human disease

I Cimmino, F Fiory, G Perruolo, C Miele… - International journal of …, 2020 - mdpi.com
Bisphenol A (BPA) is an organic synthetic compound serving as a monomer to produce
polycarbonate plastic, widely used in the packaging for food and drinks, medical devices …

EDC-2: the Endocrine Society's second scientific statement on endocrine-disrupting chemicals

AC Gore, VA Chappell, SE Fenton, JA Flaws… - Endocrine …, 2015 - academic.oup.com
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

Epigenetic inheritance: concepts, mechanisms and perspectives

I Lacal, R Ventura - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Parents' stressful experiences can influence an offspring's vulnerability to many pathological
conditions, including psychopathologies, and their effects may even endure for several …

Sex-specific placental responses in fetal development

CS Rosenfeld - Endocrinology, 2015 - academic.oup.com
The placenta is an ephemeral but critical organ for the survival of all eutherian mammals
and marsupials. It is the primary messenger system between the mother and fetus, where …

Endocrine disruptors acting on estrogen and androgen pathways cause reproductive disorders through multiple mechanisms: a review

S Amir, STA Shah, C Mamoulakis, AO Docea… - International Journal of …, 2021 - mdpi.com
Increasing contamination of the environment by toxic compounds such as endocrine
disrupting chemicals (EDCs) is one of the major causes of reproductive defects in both …

Neuro-toxic and reproductive effects of BPA

A Santoro, R Chianese, J Troisi… - Current …, 2019 - ingentaconnect.com
Background: Bisphenol A (BPA) is one of the highest volume chemicals produced
worldwide. It has recognized activity as an endocrine-disrupting chemical and has …

[HTML][HTML] Bisphenol A and human chronic diseases: current evidences, possible mechanisms, and future perspectives

R Rezg, S El-Fazaa, N Gharbi, B Mornagui - Environment international, 2014 - Elsevier
Bisphenol-A (BPA) is one of the highest volume chemicals produced worldwide, with over 6
billion pounds produced and over 100 t released into the atmosphere each year. Recent …

Epigenetic inheritance and the missing heritability

M Trerotola, V Relli, P Simeone, S Alberti - Human genomics, 2015 - Springer
Genome-wide association studies of complex physiological traits and diseases consistently
found that associated genetic factors, such as allelic polymorphisms or DNA mutations, only …

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

WH Goodson III, L Lowe, DO Carpenter… - …, 2015 - academic.oup.com
Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide,
but credible estimates from the World Health Organization and the International Agency for …

Placental trophoblast cell differentiation: physiological regulation and pathological relevance to preeclampsia

L Ji, J Brkić, M Liu, G Fu, C Peng, YL Wang - Molecular aspects of medicine, 2013 - Elsevier
The placenta is a transient organ that forms during pregnancy to support the growth and
development of the fetus. During human placental development, trophoblast cells …