Repurposing of drugs: An attractive pharmacological strategy for cancer therapeutics

A Kirtonia, K Gala, SG Fernandes, G Pandya… - Seminars in cancer …, 2021 - Elsevier
Human malignancies are one of the major health-related issues though out the world and
anticipated to rise in the future. The development of novel drugs/agents requires a huge …

The role of prostaglandins in different types of cancer

Á Jara-Gutiérrez, V Baladrón - Cells, 2021 - mdpi.com
The prostaglandins constitute a family of lipids of 20 carbon atoms that derive from
polyunsaturated fatty acids such as arachidonic acid. Traditionally, prostaglandins have …

Design concepts of half-sandwich organoruthenium anticancer agents based on bidentate bioactive ligands

WDJ Tremlett, DM Goodman, TR Steel, S Kumar… - Coordination chemistry …, 2021 - Elsevier
The small molecule anticancer agent cisplatin and its Pt (II) analogs carboplatin and
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …

New drugs are not enough-drug repositioning in oncology: An update

RG Armando, DLM Gomez… - … Journal of Oncology, 2020 - spandidos-publications.com
Drug repositioning refers to the concept of discovering novel clinical benefits of drugs that
are already known for use treating other diseases. The advantages of this are that several …

Unboxing the molecular modalities of mutagens in cancer

S Kumari, S Sharma, D Advani, A Khosla… - … Science and Pollution …, 2021 - Springer
The etiology of the majority of human cancers is associated with a myriad of environmental
causes, including physical, chemical, and biological factors. DNA damage induced by such …

Actinic keratosis–review for clinical practice

ECV de Oliveira, VRV da Motta… - International journal …, 2019 - Wiley Online Library
Actinic keratosis (AK) is a lesion that arises as a result of excessive exposure to solar
radiation and appearing predominantly on Fitzpatrick phototype I and II skin. Given that …

[BOOK][B] Profiles of drug substances, excipients, and related methodology

HG Brittain - 2020 - books.google.com
Profiles of Drug Substances, Excipients, and Related Methodology, Volume 45, presents
comprehensive reviews of drug substances and additional materials, with critical review …

Preliminary evidence of efficacy, safety, and treatment satisfaction with tirbanibulin 1% ointment: a clinical perspective on actinic keratoses

E Campione, A Rivieccio, R Gaeta Shumak… - Pharmaceuticals, 2023 - mdpi.com
Background: Actinic keratosis is a common precancerous skin lesion that can progress into
invasive squamous cell carcinomas. Many topical treatments for actinic keratoses often have …

Field cancerization therapies for management of actinic keratosis: a narrative review

N Jetter, N Chandan, S Wang, M Tsoukas - American journal of clinical …, 2018 - Springer
Actinic keratoses (AKs) are atypical, precancerous proliferations of keratinocytes that
develop because of chronic exposure to ultraviolet (UV) radiation. Treatment of AK can be …

Photosensitizing medications and skin cancer: a comprehensive review

EA George, N Baranwal, JH Kang, AA Qureshi… - Cancers, 2021 - mdpi.com
Simple Summary Photosensitizing medications are commonly used in the United States,
and studies have begun exploring whether exposure to these medications may be a risk …