Reducing food intake to induce undernutrition but not malnutrition extends the life spans of
multiple species, ranging from single-celled organisms to mammals. This increase in …

The fruit fly Drosophila is a useful organism for the investigation of the mechanisms by which
dietary restriction (DR) extends lifespan. Its relatively short generation time, well …

The idea for this book came from the time the authors spent at the Statistics and Applied
Mathematical Sciences Institute (SAMSI) in Research Triangle Park in North Carolina …

This book presents recently developed statistical methods and theory required for the
application of the tools of functional data analysis to problems arising in geosciences …

В монографии проанализированы основные концепции о природе старения, история
их возникновения и эволюция. Изложены современные представления о …

Chronic dietary restriction (DR) is considered among the most robust life‐extending
interventions, but several reports indicate that DR does not always extend and may even …

Laboratory survival experiments have shown that dietary restriction (DR) can increase
median and maximum lifespan. This paper provides a meta-analysis of laboratory …

Dietary restriction (DR) and mutations in nutrient signaling pathways can extend healthy life
span in diverse organisms. Studying the interaction between these interventions should …

Caloric restriction (CR) has been widely accepted as a mechanism explaining increased
lifespan (LS) in organisms subjected to dietary restriction (DR), but recent studies …

Various so-called dietary restriction paradigms have shown promise for extending health
and life. All such paradigms rely on ad libitum (hereafter ad lib) feeding, something virtually …