Engineered cardiac tissues derived from human induced pluripotent stem cells offer unique
opportunities for patient-specific disease modeling, drug discovery and cardiac repair. Since …

Functional polymeric micro-/nanofibers have emerged as promising materials for the
construction of structures potentially useful in biomedical fields. Among all kinds of …

Hydrogels are attractive materials for tissue engineering, but efforts to date have shown
limited ability to produce the microstructural features necessary to promote cellular self …

Creating functional tissues and organs in vitro on demand is a major goal in biofabrication,
but the ability to replicate the external geometry of specific organs and their internal …

Cellular models are needed to study human development and disease in vitro, and to
screen drugs for toxicity and efficacy. Current approaches are limited in the engineering of …

Electrospinning (e‐spin) technique has emerged as a versatile and feasible pathway for
constructing diverse polymeric fabric structures, which show potential applications in many …

Helical alignments within the heart's musculature have been speculated to be important in
achieving physiological pum** efficiencies. Testing this possibility is difficult, however …

Tissue engineering using cardiomyocytes derived from human pluripotent stem cells holds a
promise to revolutionize drug discovery, but only if limitations related to cardiac chamber …

Rationale: One goal of cardiac tissue engineering is the generation of a living, human pump
in vitro that could replace animal models and eventually serve as an in vivo therapeutic …

The ability to replicate the 3D myocardial architecture found in human hearts is a grand
challenge. Here, the fabrication of aligned cardiac tissues via bioprinting anisotropic organ …