[HTML][HTML] Validation of a novel, rapid sepsis diagnostic for emergency department use

HR O'Neal Jr, R Sheybani, DR Janz… - Critical Care …, 2024 - journals.lww.com
OBJECTIVES: To assess the in vitro IntelliSep test, a microfluidic assay that quantifies the
state of immune activation by evaluating the biophysical properties of leukocytes, as a rapid …

Cellular host response sepsis test for risk stratification of patients in the emergency department: A pooled analysis

HR O'Neal Jr, R Sheybani, CK Kraus… - Academic …, 2024 - Wiley Online Library
Objectives Sepsis is one of the most common, costly, and misdiagnosed conditions in US
emergency departments (EDs). ED providers often treat on nonspecific signs, subjective …

[HTML][HTML] Variability in Provider Assessment of Sepsis and Potential of Host Response Technology to Address this Dilemma—Results of an Online Delphi Study

CK Kraus, HR O'Neal, NA Ledeboer, TW Rice… - Journal of Personalized …, 2023 - mdpi.com
Potentially septic patients have a huge clinical and economic impact on hospitals and often
present to the emergency department (ED) with undifferentiated symptoms. The triage of …

Microfluidic creep experiment for measuring linear viscoelastic mechanical properties of microparticles in a cross-slot extensional flow device

SG Mamaghani, JB Dahl - bioRxiv, 2024 - biorxiv.org
The micromechanical measurement field has struggled to establish repeatable techniques,
likely because the deforming stresses can be complicated and difficult to model. Here we …

Accelerating the development of inertial microfluidic devices using numerical modelling and machine learning

B Owen - Frontiers in Lab on a Chip Technologies, 2024 - frontiersin.org
Inertial microfluidics allows for passive, label-free manipulation of particles suspended in a
fluid. Physical experiments can understand the underlying mechanisms to an extent …

Taking Aim at Sepsis to Save Millions From Sudden Death

L Mertz - IEEE Pulse, 2024 - ieeexplore.ieee.org
Sepsis is an urgent medical problem around the world with at least 47 million affected per
year. Of those, about a quarter—at least 11 million—die, and many sepsis survivors face …

[HTML][HTML] Taking Aim at Sepsis to Save Millions From Sudden Death April 22, 2024

L Mertz - embs.org
Taking Aim at Sepsis to Save Millions From Sudden Death https://www. embs. org/pulse/wp-
content/uploads/sites/13/2024/04/taking-aim-at-sepsis-to-save-millions-from-sudden-death …