Sepsis-induced cardiomyopathy: a comprehensive review

M L'Heureux, M Sternberg, L Brath, J Turlington… - Current Cardiology …, 2020 - Springer
Abstract Purpose of Review To briefly review epidemiology and pathophysiology of SICM
and provide a more extensive review of the data on diagnostic and management strategies …

Research progress on the mechanism and management of septic cardiomyopathy: a comprehensive review

XB Pei, B Liu - Emergency Medicine International, 2023 - Wiley Online Library
Sepsis is defined as a kind of life‐threatening organ dysfunction due to a dysregulated host
immune response to infection and is a leading cause of mortality in the intensive care unit …

Tanshinone IIA inhibits cardiomyocyte apoptosis and rescues cardiac function during doxorubicin-induced cardiotoxicity by activating the DAXX/MEK/ERK1/2 pathway

L Xu, D He, Y Wu, L Shen, Y Wang, Y Xu - Phytomedicine, 2022 - Elsevier
Background Heart failure (HF) is a common cardiovascular syndrome. Tanshinone IIA (Tan
IIA) is a pharmacologically active monomer that exerts a significant cardioprotective effect in …

[HTML][HTML] FAM134B-mediated endoplasmic reticulum autophagy protects against sepsis myocardial injury in mice

T Li, Y Chen, Y Li, Z Yao, W Liu - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Abstract Reticulophagy regulator 1 (RETEG1, also known as FAM134B) plays a crucial role
in endoplasmic reticulum autophagy. We aimed to explore the effect of FAM134B-mediated …

Tubeimoside I protects against sepsis-induced cardiac dysfunction via SIRT3

Z Cheng, D Lv, M Luo, R Wang, Y Guo, X Yang… - European Journal of …, 2021 - Elsevier
Sepsis-induced cardiac dysfunction (SICD) is one of the key complications in sepsis and it is
associated with adverse outcomes and increased mortality. There is no effective drug to treat …

Crocetin Attenuates Sepsis-Induced Cardiac Dysfunction via Regulation of Inflammatory Response and Mitochondrial Function

Y Wang, W Yu, C Shi, P Hu - Frontiers in physiology, 2020 - frontiersin.org
Sepsis-induced systemic inflammation can induce cardiac dysfunction, which can result in
heart failure and death. Recently, natural drugs/compounds have received increased …

α1-adrenoceptor stimulation ameliorates lipopolysaccharide-induced lung injury by inhibiting alveolar macrophage inflammatory responses through NF-κB and ERK1 …

Z Cong, C Yang, Z Zeng, C Wu, F Zhao… - Frontiers in …, 2023 - frontiersin.org
Introduction Catecholamines such as norepinephrine or epinephrine have been reported to
participate in the development of acute respiratory distress syndrome (ARDS) by activating …

Neohesperidin dihydrochalbazone protects against septic acute kidney injury in mice

R Yang, L Qi, W Liang - Phytomedicine, 2023 - Elsevier
Background Neohesperidin dihydrochalbazone (NHDC) shows a range of pharmacological
actions, however, in septic acute kidney injury (AKI), the effect of NHDC is little known …

Phenylephrine attenuated sepsis-induced cardiac inflammation and mitochondrial injury through an effect on the PI3K/Akt signaling pathway

H Li, K Li, Y **ng, X Tang, D Yang, X Dai… - Journal of …, 2019 - journals.lww.com
Objective: To investigate whether phenylephrine (PE) inhibits sepsis-induced cardiac
dysfunction, cardiac inflammation, and mitochondrial injury through the PI3K/Akt signaling …

Anti‐Interleukin‐16 Neutralizing Antibody Treatment Alleviates Sepsis‐Induced Cardiac Injury and Dysfunction via the Nuclear Factor Erythroid‐2 Related Factor 2 …

J Zhang, Z Yang, Z Liang, M Wang, C Hu… - Oxidative Medicine …, 2021 - Wiley Online Library
Several interleukin (IL) members have been reported to participate in sepsis. In this study,
the effects of IL‐16 on sepsis‐induced cardiac injury and dysfunction were examined, and …