Genomics and epidemiology of the P. 1 SARS-CoV-2 lineage in Manaus, Brazil

NR Faria, TA Mellan, C Whittaker, IM Claro… - Science, 2021 - science.org
Cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in
Manaus, Brazil, resurged in late 2020 despite previously high levels of infection. Genome …

COVID-19 in Amazonas, Brazil, was driven by the persistence of endemic lineages and P. 1 emergence

FG Naveca, V Nascimento, VC de Souza, AL Corado… - Nature medicine, 2021 - nature.com
The northern state of Amazonas is among the regions in Brazil most heavily affected by the
COVID-19 epidemic and has experienced two exponentially growing waves, in early and …

Evolution and epidemic spread of SARS-CoV-2 in Brazil

DS Candido, IM Claro, JG De Jesus, WM Souza… - Science, 2020 - science.org
Brazil currently has one of the fastest-growing severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) epidemics in the world. Because of limited available data …

SARS-CoV-2 variants and effectiveness of vaccines: a review of current evidence

EB Tatsi, F Filippatos, A Michos - Epidemiology & Infection, 2021 - cambridge.org
The SARS-CoV-2 virus is rapidly evolving via mutagenesis, lengthening the pandemic, and
threatening the public health. Until August 2021, 12 variants of SARS-CoV-2 named as …

Human genetic basis of coronavirus disease 2019

H Deng, X Yan, L Yuan - Signal transduction and targeted therapy, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) caused by a novel coronavirus, severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in considerable …

[HTML][HTML] SARS-CoV-2 reinfection by the new Variant of Concern (VOC) P. 1 in Amazonas, Brazil

F Naveca, C da Costa, V Nascimento, V Souza… - Virological …, 2021 - virological.org
Summary The SARS-CoV-2 lineage B. 1.1. 28 has been evolving in Brazil since February
2020, but the recent emergence of sub-lineages with convergent mutations in the spike (S) …

[HTML][HTML] Spike E484K mutation in the first SARS-CoV-2 reinfection case confirmed in Brazil, 2020

PC Resende, JF Bezerra, RHT de Vasconcelos… - Virological …, 2021 - virological.org
Summary On December 9th, the Brazilian Ministry of Health (MoH) recognised the first case
of reinfection in the country. A 37-years-old healthcare worker resident in Northeast Brazil …

Spread of Gamma (P. 1) sub-lineages carrying Spike mutations close to the furin cleavage site and deletions in the N-terminal domain drives ongoing transmission of …

FG Naveca, V Nascimento, V Souza… - Microbiology …, 2022 - Am Soc Microbiol
The Amazonas was one of the most heavily affected Brazilian states by the COVID-19
epidemic. Despite a large number of infected people, particularly during the second wave …

A potential SARS-CoV-2 variant of interest (VOI) harboring mutation E484K in the Spike protein was identified within lineage B. 1.1. 33 circulating in Brazil

PC Resende, T Gräf, ACD Paixão, L Appolinario… - Viruses, 2021 - mdpi.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic in Brazil was
dominated by two lineages designated as B. 1.1. 28 and B. 1.1. 33. The two SARS-CoV-2 …

Viral load in COVID-19 patients: implications for prognosis and vaccine efficacy in the context of emerging SARS-CoV-2 variants

SJR Silva, SC Lima, RC Silva, A Kohl, L Pena - Frontiers in Medicine, 2022 - frontiersin.org
The worldwide spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has caused an unprecedented public health crisis in the 21st century. As the pandemic …