The complexity of biological membranes has motivated the development of a wide variety of
simpler model systems whose size, geometry, and composition can be tailored with great …

Biological protein pores and pore-forming peptides can generate a pathway for the flux of
ions and other charged or polar molecules across cellular membranes. In nature, these …

Lipids and several specialized proteins are thought to be able to sense the curvature of
membranes (MC). Here we used quantitative fluorescence microscopy to measure curvature …

The plasma membrane is of central importance for defining the closed volume of cells in
contradistinction to the extracellular environment. The plasma membrane not only serves as …

Precise understanding of biological functions requires tools comparable in size to the basic
components of life,,,. Single molecule studies have revealed molecular behaviors usually …

In nature, the fusion of phospholipid vesicles is regulated and catalyzed by highly
specialized SNARE proteins. A key step in this process is to bring about close apposition of …

BAR (Bin/Amphiphysin/Rvs) domains and amphipathic α‐helices (AHs) are believed to be
sensors of membrane curvature thus facilitating the assembly of protein complexes on …

Sensitive and selective biosensors for high‐throughput screening are having an increasing
impact in modern medical care. The establishment of robust protein biosensing platforms …

By mimicking Nature's way of utilizing multivalent interactions, we introduce in the present
work a novel method to improve the strength of cholesterol-based DNA coupling to lipid …

This review is an account of our efforts to develop a versatile and flexible microfluidic
technology for surface‐processing applications and miniaturizing biological assays. The …